| TISSUE ENGINEERING AND REMODELING BIOTECHNOLOGIES FOR BODY FUNCTION |
The Board of Teachers proposes the Research Doctorate in Tissue Engineering and Remodeling Biotechnologies for Body Function with the aim of expanding knowledge at both molecular and clinical levels on the etiology, pathogenesis, and progression of acquired and/or hereditary diseases, including metabolic, degenerative, and oncological conditions. Particular attention is devoted to disorders affecting the musculoskeletal system, the maxillofacial district, the visual system, and the otorhinolaryngological field, approached from medical, surgical, sports, and rehabilitative perspectives. The program is designed to develop advanced research activities in the biotechnological and biomedical fields, with a strong focus on therapeutic and rehabilitative applications. Special emphasis is placed on chronic degenerative diseases due to their significant impact on healthcare systems. Within this framework, research projects will also address the physico-chemical properties of biomaterials aimed at extracellular matrix regeneration and remodeling, as well as the development of innovative biotechnologies for clinical applications across different body systems, in line with the diverse expertise of the Board members. The multidisciplinary composition of the Board will support the achievement of these objectives through: (a) optimization of molecular and cellular biotechnological resources; (b) development of epidemiological data biobanks; and (c) design and validation of innovative diagnostic systems, protocols, and therapeutic pathways. From an organizational perspective, the Doctorate is structured into four closely interconnected pathways, supported by multidisciplinary tutoring: (i) molecular pathophysiology, (ii) tissue engineering and extracellular matrix remodeling, (iii) clinical research for the optimization of body function, and (iv) therapeutic and rehabilitative applications. The first pathway focuses on identifying molecular mechanisms underlying diseases, particularly in the head–neck region and musculoskeletal system. The second addresses biomaterials and advanced strategies for tissue engineering and stem cell applications in orthopedics, ophthalmology, and otorhinolaryngology. The third pathway emphasizes clinical translation, integrating prior knowledge to improve functional outcomes, including in sports medicine. The fourth focuses on innovative therapeutic and rehabilitative approaches. This integrated and interdisciplinary structure ensures that each pathology or disability is investigated from multiple perspectives, ranging from molecular mechanisms to clinical and rehabilitative strategies, thereby promoting a comprehensive, multidisciplinary, and translational research approach. Different aspects will be pursued autonomously by Board members, also in relation to available funding and ongoing research projects.
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