MASSIMILIANO AGOSTINI

Associate professor

email: m.agostini@med.uniroma2.it
phone: 06 72596473

Massimliano Agostini is Associate Professor in Molecular Biology at the University of Rome “Tor Vergata”. He obtained his PhD in Clinical and Experimental Pharmacology (Perugia, Italy), working on the pharmacological regulation of the immune response. In 2005, he became a Research Assistant at University of Perugia (Italy). In 2007-2014, he worked at the MRC Toxicology Unit, (UK), as PostDoc and then as Senior Investigator. In 2014 worked at TW Mak’s laboratory as visiting scientist (Canada). From 2014 to 2019 Visiting Scientist, MRC Toxicology Unit, Cambridge University, UK.

MA is mainly interested in the characterization of transgenic mice with genetic alterations in the p53 family genes and their targets to understand their effect on development and cancer. In particular, he aims to investigate the role of the transcription factor ZNF750 (transcriptionally regulated by p63) in tumorogenesis by using in vitro and in vivo models combined with system biology (transcriptomics, proteomics and metabolomics). Currently, MA is mainly involved on:

1) To identify in-vivo functions of ZNF750 in development, physiology and tumorigenesis by using genetically modified animals.

2) Investigating the role of lipid droplets in physiology and pathophysiology.

3) Uncover novel molecular targets in lipid metabolism for cancer therapy.

Research products

2108/364728 - 2024 - Molecular profiling of a bladder cancer with very high tumour mutational burden

Scimeca, Manuel; Bonfiglio, Rita; Iacovelli, Valerio; Carilli, Marco; Agostini, Massimiliano; Rovella, Valentina; Servadei, Francesca; Giacobbi, Erica; Candi, Eleonora; Melino, Gennaro; Mauriello, Alessandro; Bove, Pierluigi - 01 - Articolo su rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 1-7 - issn: 2058-7716 - wos: WOS:001210811200002 (0) - scopus: 2-s2.0-85191817271 (0)

2108/385703 - 2024 - Thioredoxin‐interacting protein (TXNIP) is a substrate of the NEDD4‐like E3 ubiquitin‐protein ligase WWP1 in cellular redox state regulation of acute myeloid leukemia cells

Giovannini, Sara; Li, Yanan; Pecorari, Rosalba; Fierro, Claudia; Fiorilli, Claudia; Corigliano, Federica; Moriconi, Valeria; Zhou, Ji; Smirnov, Artem; Agostini, Massimiliano; Candi, Eleonora; Bernassola, Francesca - 01 - Articolo su rivista

paper: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. - - issn: 1574-7891 - wos: (0) - scopus: 2-s2.0-85205562222 (0)

2108/358103 - 2024 - Genomic and transcriptomic profiling of hepatocellular carcinoma reveals a rare molecular subtype

Rovella, Valentina; Scimeca, Manuel; Mauriello, Alessandro; Anselmo, Alessandro; Melino, Gennaro; Tisone, Giuseppe; Agostini, Massimiliano - 01 - Articolo su rivista

paper: DISCOVER ONCOLOGY ([New York]: Springer, 2021-) pp. 1-13 - issn: 2730-6011 - wos: WOS:001142329200002 (1) - scopus: 2-s2.0-85182407426 (1)

2108/358101 - 2023 - Programmed Cell Death Pathways in Cholangiocarcinoma: Opportunities for Targeted Therapy

Scimeca, Manuel; Rovella, Valentina; Scioli, Maria Paola; Bonfiglio, Rita; Piacentini, Mauro; Agostini, Massimiliano; Candi, Eleonora; Mauriello, Alessandro - 01 - Articolo su rivista

paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:001038184100001 (1) - scopus: 2-s2.0-85166191183 (1)

2108/338887 - 2023 - Harnessing metabolism of hepatic macrophages to aid liver regeneration

Scimeca, Manuel; Mauriello, Alessandro; Piacentini, Mauro; Tisone, Giuseppe; Agostini, Massimiliano - 01 - Articolo su rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. 574- - issn: 2041-4889 - wos: WOS:001057598000001 (0) - scopus: 2-s2.0-85168925772 (4)

2108/322421 - 2023 - Apoptotic cell death in disease-Current understanding of the NCCD 2023

Vitale, Ilio; Agostini, Massimiliano; Amelio, Ivano; Bernassola, Francesca; Bove, Pierluigi; Campanella, Michelangelo; Candi, Eleonora; Cecconi, Francesco; Melino, Sonia; Novelli, Flavia; Sica, Giuseppe; Vuri, Daniela; Piacentini, Mauro - 01 - Articolo su rivista

paper: CELL DEATH AND DIFFERENTIATION (Basingstoke: Nature Publishing Group.) pp. 1097-1154 - issn: 1476-5403 - wos: WOS:000992438100001 (120) - scopus: 2-s2.0-85153609153 (125)

2108/338067 - 2023 - Apoptotic cell death in disease-Current understanding of the NCCD 2023

Vitale, Ilio; Agostini, Massimiliano; Amelio, Ivano; Sica, Giuseppe; Bernassola, Francesca; Bove, Pierluigi; Campanella, Michelangelo; Candi, Eleonora; Cecconi, Francesco; Ganini, Carlo; Manic, Gwenola; Melino, Sonia; Novelli, Flavia; Sesti, Franz Federico; Vuri, Daniela; Piacentini, Mauro - 01 - Articolo su rivista

paper: CELL DEATH AND DIFFERENTIATION (Basingstoke: Nature Publishing Group.) pp. 1097-1154 - issn: 1476-5403 - wos: WOS:000992438100001 (105) - scopus: 2-s2.0-85153609153 (128)

2108/322380 - 2023 - ZNF750: A Novel Prognostic Biomarker in Metastatic Prostate Cancer

Montanaro, Manuela; Agostini, Massimiliano; Anemona, Lucia; Bonanno, Elena; Servadei, Francesca; Cipriani, Chiara; Bove, Pierluigi; Melino, Gennaro; Mauriello, Alessandro; Scimeca, Manuel - 01 - Articolo su rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-15 - issn: 1422-0067 - wos: WOS:000969854500001 (1) - scopus: 2-s2.0-85152323429 (1)

2108/358102 - 2023 - Alleviating hypoxia to improve cancer immunotherapy

Fan, Peng; Candi, Eleonora; Agostini, Massimiliano; Piacentini, Mauro; Bernassola, Francesca; Bove, Pierluigi; Mauriello, Alessandro; Novelli, Giuseppe; Rovella, Valentina; Scimeca, Manuel; Sica, Giuseppe; Tisone, Giuseppe - 01 - Articolo su rivista

paper: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 3591-3604 - issn: 1476-5594 - wos: WOS:001090692400001 (16) - scopus: 2-s2.0-85174966254 (14)

2108/358100 - 2023 - ZFP750 affects the cutaneous barrier through regulating lipid metabolism

Butera, Alessio; Agostini, Massimiliano; Cassandri, Matteo; Falasca, Laura; Piacentini, Mauro; Candi, Eleonora - 01 - Articolo su rivista

paper: SCIENCE ADVANCES (Washington, DC : American Association for the Advancement of Science, 2015-) pp. - - issn: 2375-2548 - wos: WOS:000988217400003 (8) - scopus: 2-s2.0-85159243686 (8)

2108/304134 - 2022 - Targeting lipid metabolism in cancer: neuroblastoma

Agostini, Massimiliano - 01 - Articolo su rivista

paper: CANCER AND METASTASIS REVIEWS (NEW YORK, NY: SPRINGER Dordrecht: Kluwer) pp. 255-260 - issn: 1573-7233 - wos: WOS:000809301800001 (6) - scopus: 2-s2.0-85131662961 (5)

2108/322381 - 2022 - Long non-coding RNAs affecting cell metabolism in cancer

Agostini, Massimiliano; Candi, Eleonora - 01 - Articolo su rivista

paper: BIOLOGY DIRECT (London: BioMed Central) pp. 1-12 - issn: 1745-6150 - wos: WOS:000862559000001 (12) - scopus: 2-s2.0-85139154253 (12)

2108/290475 - 2022 - Correction to: The expression of {ELOVL}4, repressed by {MYCN}, defines neuroblastoma patients with good outcome

Melino, Gennaro; Agostini, Massimiliano - 01 - Articolo su rivista

paper: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 1386-1387 - issn: 1476-5594 - wos: WOS:000744835300001 (0) - scopus: 2-s2.0-85123166769 (0)

2108/290473 - 2021 - The expression of {ELOVL}4, repressed by {MYCN}, defines neuroblastoma patients with good outcome

Melino, Gennaro; Agostini, Massimiliano - 01 - Articolo su rivista

paper: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 5741-5751 - issn: 1476-5594 - wos: WOS:000679771600001 (15) - scopus: 2-s2.0-85111631321 (14)

2108/291507 - 2021 - {TAp}63 regulates bone remodeling by modulating the expression of {TNFRSF}11B/Osteoprotegerin

Lena, Anna Maria; Agostini, Massimiliano; Mancini, Mara; Melino, Gennaro; Candi, Eleonora - 01 - Articolo su rivista

paper: CELL CYCLE (Austin, TX : Landes Bioscience Georgetown, TX : Landes Bioscience, c2002-) pp. 2428-2441 - issn: 1551-4005 - wos: WOS:000717873000001 (1) - scopus: 2-s2.0-85119299500 (1)

2108/290390 - 2021 - Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin

Xie, Ningxia; Candi, Eleonora; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH AND DIFFERENTIATION (Basingstoke: Nature Publishing Group.) pp. 156-169 - issn: 1476-5403 - wos: WOS:000551001800002 (41) - scopus: 2-s2.0-85088237094 (36)

2108/280607 - 2020 - Regulation of Adult Neurogenesis in Mammalian Brain

Agostini, Massimiliano; Amelio, Ivano; Melino, Gennaro - 01 - Articolo su rivista

paper: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 1-21 - issn: 1422-0067 - wos: WOS:000557427500001 (80) - scopus: 2-s2.0-85088051186 (85)

2108/280609 - 2020 - The role of noncoding RNAs in epithelial cancer

Agostini, Massimiliano; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 13- - issn: 2058-7716 - wos: WOS:000519430700001 (33) - scopus: 2-s2.0-85081734199 (39)

2108/280611 - 2020 - ZNF750 represses breast cancer invasion via epigenetic control of prometastatic genes

Cassandri, Matteo; Amelio, Ivano; Lena, Anna Maria; Montanaro, Manuela; Mauriello, Alessandro; Anemona, Lucia; Candi, Eleonora; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 4331-4343 - issn: 1476-5594 - wos: WOS:000527509300003 (29) - scopus: 2-s2.0-85083706898 (32)

2108/280613 - 2020 - The ZNF750-RAC1 axis as potential prognostic factor for breast cancer

Cassandri, Matteo; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 135- - issn: 2058-7716 - wos: WOS:000594209600001 (12) - scopus: 2-s2.0-85096911174 (13)

2108/280615 - 2020 - The C terminus of p73 is essential for hippocampal development

Amelio, Ivano; Panatta, Emanuele; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 15694-15701 - issn: 1091-6490 - wos: WOS:000548347200021 (18) - scopus: 2-s2.0-85088207956 (18)

2108/233644 - 2018 - ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma

Pieraccioli, Marco; Pitolli, Consuelo; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 7356-7361 - issn: 1091-6490 - wos: WOS:000438050900072 (35) - scopus: 2-s2.0-85049607531 (36)

2108/233636 - 2018 - The p53 Family in Brain Disease

Agostini, Massimiliano; Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista

paper: ANTIOXIDANTS & REDOX SIGNALING ([Larchmont, NY] : Mary Ann Liebert, Inc.) pp. 1-14 - issn: 1557-7716 - wos: WOS:000417247800001 (12) - scopus: 2-s2.0-85038914799 (12)

2108/233646 - 2018 - Sustained protein synthesis and reduced eEF2K levels in TAp73-- mice brain: a possible compensatory mechanism

Agostini, Massimiliano; Amelio, Ivano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL CYCLE (Austin, TX : Landes Bioscience Georgetown, TX : Landes Bioscience, c2002-) pp. 2637-2643 - issn: 1551-4005 - wos: WOS:000454454700010 (3) - scopus: 2-s2.0-85058099993 (3)

2108/294562 - 2018 - p73 Regulates Primary Cortical Neuron Metabolism: a Global Metabolic Profile

Agostini, Massimiliano; Grelli, Sandro; Di Daniele, Nicola; Pestlikis, Ilias; Melino, Gennaro - 01 - Articolo su rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 3237-3250 - issn: 0893-7648 - wos: WOS:000427097500041 (8) - scopus: 2-s2.0-85018752815 (9)

2108/194613 - 2018 - p73 Regulates Primary Cortical Neuron Metabolism: a Global Metabolic Profile

Agostini, Massimiliano; Di Daniele, Nicola; Pestlikis, Ilias; Melino, Gennaro - 01 - Articolo su rivista

2108/233642 - 2017 - Zinc-finger proteins in health and disease

Cassandri, Matteo; Smirnov, Artem; Novelli, Flavia; Pitolli, Consuelo; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 17071- - issn: 2058-7716 - wos: WOS:000463082900090 (480) - scopus: 2-s2.0-85047875942 (501)

2108/226859 - 2017 - Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells

Diso, Daniele; Amelio, Ivano; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CANCER LETTERS (Elsevier Science Ireland Limited:PO Box 85, Limerick Ireland:011 353 61 709600, 011 353 61 61944, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 353 61 709114) pp. 93-104 - issn: 0304-3835 - wos: WOS:000412265000011 (90) - scopus: 2-s2.0-85027985288 (100)

2108/261218 - 2016 - C-reactive protein levels in the perioperative period as a predictive marker of endoscopic recurrence after ileo-colonic resection for Crohn's disease

Iaculli, Edoardo; Agostini, Massimiliano; Biancone, Livia; Manzelli, Antonio; Tesauro, Manfredi; Sica, Giuseppe - 01 - Articolo su rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 16032- - issn: 2058-7716 - wos: WOS:000463076300035 (15) - scopus: 2-s2.0-85020485372 (14)

2108/207771 - 2016 - Metabolic pathways regulated by TAp73 in response to oxidative stress

Agostini, Massimiliano - 01 - Articolo su rivista

paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 29881-900-29900 - issn: 1949-2553 - wos: WOS:000377746600004 (20) - scopus: 2-s2.0-84971569618 (22)

2108/233634 - 2016 - Metabolic reprogramming during neuronal differentiation

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH AND DIFFERENTIATION (Basingstoke: Nature Publishing Group.) pp. 1502-1514 - issn: 1476-5403 - wos: WOS:000381072800008 (178) - scopus: 2-s2.0-84964047281 (187)

2108/173468 - 2016 - C-reactive protein levels in the perioperative period as a predictive marker of endoscopic recurrence after ileo-colonic resection for Crohn's disease.

Iaculli, Edoardo; Agostini, Massimiliano; Biancone, Livia; Tesauro, Manfredi; Sica, Giuseppe - 01 - Articolo su rivista

paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. - - issn: 2058-7716 - wos: WOS:000463076300035 (10) - scopus: 2-s2.0-85020485372 (9)

2108/153228 - 2016 - How Does p73 Cause Neuronal Defects?

Melino, Gennaro; Agostini, Massimiliano - 01 - Articolo su rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 4509-4520 - issn: 0893-7648 - wos: WOS:000380678600020 (23) - scopus: 2-s2.0-84939214694 (24)

2108/158017 - 2015 - Progesterone and Melanoma Cells: An Old Story Suspended between Life and Death

Gaziano, Roberta; Bue', Maria Cristina; Agostini, Massimiliano; Perno, Carlo-Federico; Sinibaldi, Paola; Pica, Francesca - 01 - Articolo su rivista

paper: JOURNAL OF STEROIDS & HORMONAL SCIENCE (Los Angeles, CA : OMICS Publishing Group) pp. - - issn: 2157-7536 - wos: (0) - scopus: (0)

2108/153208 - 2015 - p73 regulates basal and starvation-induced liver metabolism in vivo

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 33178-33190 - issn: 1949-2553 - wos: WOS:000363186600081 (17) - scopus: 2-s2.0-84946056227 (16)

2108/153187 - 2015 - TAp73 transcriptionally represses BNIP3 expression

Agostini, Massimiliano; Melino, Gennaro; Amelio, Ivano - 01 - Articolo su rivista

paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 2484-2493 - issn: 1538-4101 - wos: WOS:000359768900019 (15) - scopus: 2-s2.0-84943782434 (16)

2108/238695 - 2015 - MicroRNAs and p63 in epithelial stemness

Candi, Eleonora; Amelio, Ivano; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 12-21 - issn: 1350-9047 - wos: WOS:000347841600004 (61) - scopus: 2-s2.0-84926612721 (65)

2108/238573 - 2015 - microRNAs and p63 in epithelial stemness

Candi, Eleonora; Amelio, Ivano; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

2108/153167 - 2015 - P63 supports aerobic respiration through hexokinase II

Agostini, Massimiliano; Lena, Anna Maria; Melino, Gennaro; Candi, Eleonora - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 11577-11582 - issn: 0027-8424 - wos: WOS:000361393700050 (63) - scopus: 2-s2.0-84941696058 (69)

2108/131985 - 2014 - Serine and glycine metabolism in cancer

Amelio, Ivano; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: TRENDS IN BIOCHEMICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 191-198 - issn: 0968-0004 - wos: WOS:000335426200007 (737) - scopus: 2-s2.0-84897392385 (756)

2108/131992 - 2014 - p73 regulates serine biosynthesis in cancer

Amelio, Ivano; Tucci, Paola; Agostini, Massimiliano; Mineo, Tommaso Claudio; Melino, Gennaro - 01 - Articolo su rivista

paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 5039-5046 - issn: 0950-9232 - wos: WOS:000343768000008 (91) - scopus: 2-s2.0-84961390534 (97)

2108/127392 - 2014 - miR-34: From bench to bedside

Agostini, Massimiliano - 01 - Articolo su rivista

paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 872-881 - issn: 1949-2553 - wos: WOS:000336962300002 (215) - scopus: 2-s2.0-84897410547 (233)

2108/120054 - 2014 - Bioinformatics analysis of the serine and glycine pathway in cancer cells

Agostini, Massimiliano; Morello, Maria; Minieri, Marilena; Melino, Gennaro; Amelio, Ivano - 01 - Articolo su rivista

paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 11004-11013 - issn: 1949-2553 - wos: WOS:000348037400010 (66) - scopus: 2-s2.0-84917690907 (66)

2108/132075 - 2014 - TAp73 is required for spermatogenesis and the maintenance of male fertility

Agostini, Massimiliano; Amelio, Ivano; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (Editore National Academy of Sciences a Washington, DC) pp. 1843-1848 - issn: 1091-6490 - wos: WOS:000330587600052 (70) - scopus: 2-s2.0-84893467658 (78)

2108/113670 - 2014 - How the TP53 Family Proteins TP63 and TP73 contribute to tumorigenesis: Regulators and effectors

Candi, Eleonora; Agostini, Massimiliano; Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista

paper: HUMAN MUTATION (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 702-714 - issn: 1059-7794 - wos: WOS:000336618900007 (115) - scopus: 2-s2.0-84901244771 (121)

2108/128912 - 2014 - TAp73 promotes anti-senescence-anabolism not proliferation

Agostini, Massimiliano; Catani, Maria Valeria; Melino, Gennaro - 01 - Articolo su rivista

paper: AGING (Impact Journals LLC) pp. 921-930 - issn: 1945-4589 - wos: WOS:000348055200002 (18) - scopus: 2-s2.0-84920271599 (18)

2108/102713 - 2013 - p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1415-1424 - issn: 1350-9047 - wos: WOS:000324301700016 (72) - scopus: 2-s2.0-84883776970 (75)

2108/102718 - 2013 - Rapamycin regulates biochemical metabolites

Tucci, Paola; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 2454-2467 - issn: 1538-4101 - wos: WOS:000327437400022 (9) - scopus: 2-s2.0-84881524770 (7)

2108/102690 - 2013 - GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation

Romeo, Francesco; Tucci, Paola; Amelio, Ivano; Melino, Gennaro; Agostini, Massimiliano - 01 - Articolo su rivista

paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 3564-3573 - issn: 1538-4101 - wos: WOS:000330526200019 (78) - scopus: 2-s2.0-84890403623 (79)

2108/102782 - 2013 - p63 regulates glutaminase 2 expression

Bernassola, Francesca; Terrinoni, Alessandro; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 1395-1405 - issn: 1538-4101 - wos: WOS:000322758600014 (73) - scopus: 2-s2.0-84877127022 (76)

2108/102892 - 2013 - Analysis of the oligomeric state and transactivation potential of TAp73α

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1008-1016 - issn: 1350-9047 - wos: WOS:000321425500009 (34) - scopus: 2-s2.0-84880298343 (35)

2108/102756 - 2013 - TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 18952-18957 - issn: 0027-8424 - wos: WOS:000327100600061 (48) - scopus: 2-s2.0-84888082989 (48)

2108/102872 - 2013 - Metabolic effects of TiO2 nanoparticles, a common component of sunscreens and cosmetics, on human keratinocytes

Tucci, Paola; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: CELL DEATH & DISEASE (Nature Group) pp. e549-e549 - issn: 2041-4889 - wos: WOS:000316868700028 (121) - scopus: 2-s2.0-84875895164 (137)

2108/127834 - 2012 - Embryonic stem cells and inducible pluripotent stem cells: two faces of the same coin?

Agostini, Massimiliano - 01 - Articolo su rivista

paper: AGING (Impact Journals LLC) pp. 878-886 - issn: 1945-4589 - wos: WOS:000315981800005 (6) - scopus: 2-s2.0-84874794920 (8)

2108/78435 - 2012 - Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

Agostini, Massimiliano; Terrinoni, Alessandro; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 15312-15317 - issn: 0027-8424 - wos: WOS:000331396500089 (0) - scopus: 2-s2.0-84866546174 (241)

2108/78443 - 2012 - Relative expression of TAp73 and ΔNp73 isoforms

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: AGING (Impact Journals LLC) pp. 202-205 - issn: 1945-4589 - wos: WOS:000303240500007 (32) - scopus: 2-s2.0-84863307217 (31)

2108/127841 - 2011 - Cell death pathology: Perspective for human diseases

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 451-455 - issn: 0006-291X - wos: WOS:000298519500002 (44) - scopus: 2-s2.0-80054884802 (51)

2108/127838 - 2011 - P73 in cancer

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: GENES & CANCER (Thousand Oaks, CA: SAGE Publications) pp. 491-502 - issn: 1947-6019 - wos: (0) - scopus: 2-s2.0-80052989887 (130)

2108/53944 - 2011 - microRNA-34a regulates neurite outgrowth, spinal morphology, and function

Agostini, Massimiliano; Tucci, Paola; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 21099-21104 - issn: 0027-8424 - wos: WOS:000298479900049 (161) - scopus: 2-s2.0-84855495456 (168)

2108/53456 - 2011 - miR-146a is modulated in human endothelial cell with aging

Tucci, Paola; Menghini, Rossella; Agostini, Massimiliano; Melino, Gennaro; Federici, Massimo - 01 - Articolo su rivista

paper: ATHEROSCLEROSIS (Tokyo; Oxford; New York; Lausanne; Shannon; Amsterdam: Elsevier) pp. 326-330 - issn: 0021-9150 - wos: WOS:000293212400005 (162) - scopus: 2-s2.0-79960686440 (169)

2108/127831 - 2011 - p73: A multifunctional protein in neurobiology

Melino, Gennaro; Agostini, Massimiliano - 01 - Articolo su rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 139-146 - issn: 0893-7648 - wos: WOS:000288714100009 (63) - scopus: 2-s2.0-79958706113 (66)

2108/127825 - 2011 - Ageing, neuronal connectivity and brain disorders: An unsolved ripple effect

Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: MOLECULAR NEUROBIOLOGY (Humana Press Incorporated:999 Riverview Drive, Suite 208:Totowa, NJ 07512:(973)256-1699, EMAIL: lglasner@humanapr.com, INTERNET: http://www.humanapress.com, Fax: (973)256-8341) pp. 124-130 - issn: 0893-7648 - wos: WOS:000288714100007 (29) - scopus: 2-s2.0-79958718254 (36)

2108/53946 - 2011 - Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

Agostini, Massimiliano; Tucci, Paola; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 21093-21098 - issn: 0027-8424 - wos: WOS:000298479900048 (159) - scopus: 2-s2.0-84855490109 (165)

2108/43716 - 2011 - P63 in tooth development

Barlattani, Alberto; Docimo, Raffaella; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 1256-1261 - issn: 0006-2952 - wos: WOS:000296414400002 (10) - scopus: 2-s2.0-80054696189 (12)

2108/18829 - 2010 - p73 regulates maintenance of neural stem cell

Agostini, Massimiliano; Tucci, Paola; Melino, Gennaro - 01 - Articolo su rivista

paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 13-17 - issn: 0006-291X - wos: WOS:000285226500003 (58) - scopus: 2-s2.0-78649717018 (60)

2108/18824 - 2010 - miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro

Tucci, Paola; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista

paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 921-927 - issn: 0006-291X - wos: WOS:000276986400011 (108) - scopus: 2-s2.0-77950859070 (117)

2108/19503 - 2010 - Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2

Tucci, Paola; Piro, Maria Cristina; Agostini, Massimiliano; Bernardini, Sergio; Melino, Gennaro - 01 - Articolo su rivista

paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 12877-12882 - issn: 0027-8424 - wos: WOS:000280144500033 (70) - scopus: 2-s2.0-77955648341 (73)

2108/16100 - 2009 - p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia

Agostini, Massimiliano; Bernardini, Sergio; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista

paper: BLOOD (New York: Elsevier Inc. Philadelphia, Pa.: W.B. Saunders Washington, DC : American Society of Hematology) pp. 6498-6499 - issn: 1528-0020 - wos: WOS:000267147400036 (10) - scopus: 2-s2.0-67650632619 (10)