FRANCESCA BERNASSOLA

Associate professor


email: bernasso@uniroma2.it
phone: 200101




Francesca Bernassola is professor of Molecular Biology (SSD BIO/11) at the Department of Experimental Medicine of “Tor Vergata” University. She was previously a Research Assistant at the IDI-IRCCS Biochemistry Laboratory. After receiving her PhD Degree in “Epithelia Biology and Physiopatology” at the University of Rome “Tor Vergata”, she did her postdoctoral training at the Memorial Sloan-Kettering Cancer Center, New York, USA (2001-2003) in the laboratory directed by Dr Pier Paolo Pandolfi. Her research interests are primarily directed towards studying the contribution of the E3 ubiquitin ligase WWP1 to the pathogenesis and progression of acute myeloid leukaemia. Specifically, her group seeks to investigate the effects of WWP1 inhibition on leukaemia growth and chemotherapy sensitivity and to identify and characterize novel WWP1 protein substrates mediating its oncogenic activities in leukemic blasts. She has published 66 peer-reviewed papers (total Impact Factor 519.999; Corresponding Author in 15 articles).


Research products

2108/379803 - 2024 - A comprehensive molecular characterization of a claudin-low luminal B breast tumor
Giovannini, Sara; Smirnov, Artem; Concetti, Livia; Scimeca, Manuel; Mauriello, Alessandro; Rovella, Valentina; Buonomo, Oreste Claudio; Candi, Eleonora; Bernassola, Francesca - 01 - Articolo su rivista
paper: BIOLOGY DIRECT (London: BioMed Central) pp. 1-13 - issn: 1745-6150 - wos: WOS:001291995000001 (0) - scopus: 2-s2.0-85201364287 (0)

2108/385703 - 2024 - Thioredoxin‐interacting protein (TXNIP) is a substrate of the NEDD4‐like E3 ubiquitin‐protein ligase WWP1 in cellular redox state regulation of acute myeloid leukemia cells
Giovannini, Sara; Li, Yanan; Pecorari, Rosalba; Fierro, Claudia; Fiorilli, Claudia; Corigliano, Federica; Moriconi, Valeria; Zhou, Ji; Smirnov, Artem; Agostini, Massimiliano; Candi, Eleonora; Bernassola, Francesca - 01 - Articolo su rivista
paper: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. - - issn: 1574-7891 - wos: (0) - scopus: 2-s2.0-85205562222 (0)

2108/342743 - 2023 - Macrophage polarization and metabolism in atherosclerosis
Liu, Zhanhong; Agostini, Massimiliano; Bernassola, Francesca; Bove, Pierluigi; Candi, Eleonora; Rovella, Valentina; Sica, Giuseppe; Scimeca, Manuel; Federici, Massimo; Mauriello, Alessandro - 01 - Articolo su rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. 691- - issn: 2041-4889 - wos: (0) - scopus: 2-s2.0-85174566473 (40)

2108/360504 - 2023 - p63 orchestrates serine and one carbon metabolism enzymes expression in head and neck cancer
Cappello, Angela; Tosetti, Giulia; Smirnov, Artem; Ganini, Carlo; Bernassola, Francesca; Candi, Eleonora - 01 - Articolo su rivista
paper: BIOLOGY DIRECT (London: BioMed Central) pp. 1-12 - issn: 1745-6150 - wos: WOS:001099161700001 (3) - scopus: 2-s2.0-85176097165 (3)

2108/360503 - 2023 - Involvement of transcribed lncRNA uc.291 in hyperproliferative skin disorders
Mancini, Mara; Sergio, Simone; Cappello, Angela; Bernassola, Francesca; Candi, Eleonora - 01 - Articolo su rivista
paper: BIOLOGY DIRECT (London: BioMed Central) pp. - - issn: 1745-6150 - wos: WOS:001119739400001 (1) - scopus: 2-s2.0-85178216947 (0)

2108/338025 - 2023 - Aged mesenchymal stem cells and inflammation: from pathology to potential therapeutic strategies
Rovella, Valentina; Candi, Eleonora; Bernassola, Francesca; Bove, Pierluigi; Piacentini, Mauro; Scimeca, Manuel; Sica, Giuseppe; Tisone, Giuseppe; Mauriello, Alessandro - 01 - Articolo su rivista
paper: BIOLOGY DIRECT (London: BioMed Central) pp. 40- - issn: 1745-6150 - wos: WOS:001028737200001 (7) - scopus: 2-s2.0-85165265515 (8)

2108/338067 - 2023 - Apoptotic cell death in disease-Current understanding of the NCCD 2023
Vitale, Ilio; Agostini, Massimiliano; Amelio, Ivano; Sica, Giuseppe; Bernassola, Francesca; Bove, Pierluigi; Campanella, Michelangelo; Candi, Eleonora; Cecconi, Francesco; Ganini, Carlo; Manic, Gwenola; Melino, Sonia; Novelli, Flavia; Sesti, Franz Federico; Vuri, Daniela; Piacentini, Mauro - 01 - Articolo su rivista
paper: CELL DEATH AND DIFFERENTIATION (Basingstoke: Nature Publishing Group.) pp. 1097-1154 - issn: 1476-5403 - wos: WOS:000992438100001 (105) - scopus: 2-s2.0-85153609153 (128)

2108/322421 - 2023 - Apoptotic cell death in disease-Current understanding of the NCCD 2023
Vitale, Ilio; Agostini, Massimiliano; Amelio, Ivano; Bernassola, Francesca; Bove, Pierluigi; Campanella, Michelangelo; Candi, Eleonora; Cecconi, Francesco; Melino, Sonia; Novelli, Flavia; Sica, Giuseppe; Vuri, Daniela; Piacentini, Mauro - 01 - Articolo su rivista
paper: CELL DEATH AND DIFFERENTIATION (Basingstoke: Nature Publishing Group.) pp. 1097-1154 - issn: 1476-5403 - wos: WOS:000992438100001 (120) - scopus: 2-s2.0-85153609153 (125)

2108/341183 - 2023 - A BRCA2 germline mutation and high expression of immune checkpoints in a TNBC patient
Han, Yuyi; Rovella, Valentina; Smirnov, Artem; Buonomo, Oreste Claudio; Sica, Giuseppe; Perretta, Tommaso; Candi, Eleonora; Bernassola, Francesca - 01 - Articolo su rivista
paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 1-9 - issn: 2058-7716 - wos: WOS:001080768600001 (4) - scopus: 2-s2.0-85173672522 (6)

2108/341185 - 2023 - A primary luminal/HER2 negative breast cancer patient with mismatch repair deficiency
Smirnov, Artem; Buonomo, Oreste Claudio; Sica, Giuseppe; Mauriello, Alessandro; Candi, Eleonora; Bernassola, Francesca - 01 - Articolo su rivista
paper: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. 1-8 - issn: 2058-7716 - wos: WOS:001081938200001 (6) - scopus: 2-s2.0-85173778309 (6)

2108/360523 - 2023 - p63: a crucial player in epithelial stemness regulation
Li, Yanan; Giovannini, Sara; Candi, Eleonora; Bernassola, Francesca - 01 - Articolo su rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3371-3384 - issn: 0950-9232 - wos: WOS:001087966600002 (7) - scopus: 2-s2.0-85174586599 (11)

2108/358102 - 2023 - Alleviating hypoxia to improve cancer immunotherapy
Fan, Peng; Candi, Eleonora; Agostini, Massimiliano; Piacentini, Mauro; Bernassola, Francesca; Bove, Pierluigi; Mauriello, Alessandro; Novelli, Giuseppe; Rovella, Valentina; Scimeca, Manuel; Sica, Giuseppe; Tisone, Giuseppe - 01 - Articolo su rivista
paper: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 3591-3604 - issn: 1476-5594 - wos: WOS:001090692400001 (16) - scopus: 2-s2.0-85174966254 (14)

2108/360944 - 2022 - Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors
Bernassola, Francesca; Abrignani, Sergio - 01 - Articolo su rivista
paper: IMMUNITY (Cell Press:1100 Massachusetts Avenue:Cambridge, MA 02138:(617)661-7057, EMAIL: subs@cell.com, INTERNET: http://www.cellpress.com, Fax: (617)397-2850) pp. 606-622 - issn: 1074-7613 - wos: WOS:000788864600008 (8) - scopus: 2-s2.0-85127639305 (8)

2108/360943 - 2022 - Distinct interactors define the p63 transcriptional signature in epithelial development or cancer
Pecorari, Rosalba; Bernassola, Francesca; Candi, Eleonora - 01 - Articolo su rivista
paper: BIOCHEMICAL JOURNAL (London: Portland Press Limited London: Biochemical Society, 1984-) pp. 1375-1392 - issn: 0264-6021 - wos: WOS:000818515600003 (14) - scopus: 2-s2.0-85133102200 (14)

2108/294476 - 2021 - Emerging roles of the HECT-type E3 ubiquitin ligases in hematological malignancies
Fierro, Claudia; Giovannini, Sara; Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista
paper: DISCOVER ONCOLOGY ([New York]: Springer, 2021-) pp. 39- - issn: 2730-6011 - wos: WOS:000705218600001 (4) - scopus: 2-s2.0-85116864586 (5)

2108/290238 - 2021 - Emerging roles of long non-coding RNAs in breast cancer biology and management
Amelio, Ivano; Bernassola, Francesca; Candi, Eleonora - 01 - Articolo su rivista
paper: SEMINARS IN CANCER BIOLOGY (Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010) pp. 36-45 - issn: 1044-579X - wos: WOS:000651889400006 (46) - scopus: 2-s2.0-85089734818 (43)

2108/281212 - 2020 - The impact of the ubiquitin system in the pathogenesis of squamous cell carcinomas
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000549391900001 (13) - scopus: 2-s2.0-85088609718 (11)

2108/258728 - 2020 - DHA Affects Microtubule Dynamics Through Reduction of Phospho-TCTP Levels and Enhances the Antiproliferative Effect of T-DM1 in Trastuzumab-Resistant HER2-Positive Breast Cancer Cell Lines
D'amico, Silvia; Ranalli, Marco; Gambacurta, Alessandra; Bernassola, Francesca - 01 - Articolo su rivista
paper: CELLS (Basel: mdpi-Molecular Diversity Preservation International) pp. - - issn: 2073-4409 - wos: WOS:000539340200194 (15) - scopus: 2-s2.0-85085157116 (13)

2108/228232 - 2019 - HECT-Type E3 Ubiquitin Ligases in Cancer
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: TRENDS IN BIOCHEMICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 1057-1075 - issn: 0968-0004 - wos: WOS:000496996000007 (28) - scopus: 2-s2.0-85073164417 (26)

2108/235213 - 2019 - Emerging roles of HECT-type E3 ubiquitin ligases in autophagy regulation.
Melino, Gennaro; Cecconi, Francesco; Bernassola, Francesca - 01 - Articolo su rivista
paper: MOLECULAR ONCOLOGY (Amsterdam : Elsevier Science) pp. 2033-2048 - issn: 1574-7891 - wos: WOS:000486660500001 (10) - scopus: 2-s2.0-85071837331 (11)

2108/360945 - 2019 - HECT-Type E3 Ubiquitin Ligases in Cancer
Bernassola, Francesca - 01 - Articolo su rivista
paper: TRENDS IN BIOCHEMICAL SCIENCES (Elsevier Trends Journals:An Imprint of Elsevier Science Limited, The Boulevard, Langford Lane, Kidlington, Oxford 0X5 1GB United Kingdom:011 44 1865 843000, 011 44 1865 843699, Fax: 011 44 1865 843010) pp. 1057-1075 - issn: 0968-0004 - wos: WOS:000705218600001 (5) - scopus: 2-s2.0-85073164417 (63)

2108/236392 - 2018 - ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma
Frezza, Valentina; Fierro, Claudia; Candi, Eleonora; Anemona, Lucia; Mauriello, Alessandro; Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista
paper: AGING (Impact Journals LLC) pp. 4224-4240 - issn: 1945-4589 - wos: WOS:000454633200051 (11) - scopus: 2-s2.0-85059311209 (11)

2108/208143 - 2018 - The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia
Lavorgna, Serena; Lo Coco, Francesco; Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista
paper: LEUKEMIA (-, LONDON, ENGLAND: NATURE PUBLISHING GROUP, -London,United Kingdom: Macmillan Magazines Limited -[Baltimore, Md.] : Williams & Wilkins, [c1987]-) pp. 911-919-919 - issn: 0887-6924 - wos: WOS:000429129100007 (33) - scopus: 2-s2.0-85044669597 (33)

2108/201030 - 2018 - Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018
Vitale, Ilio; Amelio, Ivano; Bernassola, Francesca; Campanella, Michelangelo; Candi, Eleonora; Cecconi, Francesco; De Laurenzi, Vincenzo; Di Daniele, Nicola; Melino, Sonia; Melino, Gennaro - 01 - Articolo su rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 486-541 - issn: 1350-9047 - wos: WOS:000426395800006 (3956) - scopus: 2-s2.0-85036533976 (4367)

2108/233636 - 2018 - The p53 Family in Brain Disease
Agostini, Massimiliano; Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista
paper: ANTIOXIDANTS & REDOX SIGNALING ([Larchmont, NY] : Mary Ann Liebert, Inc.) pp. 1-14 - issn: 1557-7716 - wos: WOS:000417247800001 (12) - scopus: 2-s2.0-85038914799 (12)

2108/185101 - 2017 - Structural evolution and dynamics of the p53 proteins
Bernassola, Francesca; Desideri, Alessandro; Melino, Gennaro - 01 - Articolo su rivista
paper: COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (Woodbury, NY : Cold Spring Harbor Laboratory Press, c2011-) pp. a028308- - issn: 2157-1422 - wos: WOS:000402171500010 (38) - scopus: 2-s2.0-85017258377 (45)

2108/236394 - 2016 - Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development.
Bernassola, Francesca - 01 - Articolo su rivista
paper: THE JOURNAL OF CLINICAL INVESTIGATION (American Society for Clinical Investigation:PO Box 7226:Ann Arbor, MI 48107:(734)222-6050, EMAIL: rhickman@the-jci.org, INTERNET: http://www.jci.org, Fax: (734)222-6058) pp. 2452-2464 - issn: 0021-9738 - wos: WOS:000379094800012 (23) - scopus: 2-s2.0-84978410600 (26)

2108/316860 - 2016 - Erratum
Amelio, Ivano; Antonioli, Manuela; Aquilano, Katia; Bernassola, Francesca; Bordi, Matteo; Campanella, Michelangelo; Campello, Silvia; Cecconi, Francesco; Cianfanelli, Valentina; Ciriolo, Maria Rosa; Corazzari, Marco; De Zio, Daniela; Di Bartolomeo, Sabrina; Di Daniele, Nicola; Di Renzo, Laura; Filomeni, Giuseppe; Frezza, Caterina; Marino, Maria Giulia; Melino, Gennaro; Melino, Sonia; Menghini, Rossella; Palumbo, Camilla; Pavone, Antonello Francesco; Piacentini, Mauro; Radogna, Flavia; Schiavi, Alfonso; Ventura, Natascia; Ventura, Silvia; Viola, Giuseppe; Viscomi, Maria Teresa - 01 - Articolo su rivista
paper: AUTOPHAGY (Philadelphia PA: Taylor & Francis Group LLC Georgetown TX: Landes Bioscience) pp. 443-443 - issn: 1554-8635 - wos: WOS:000373982600022 (403) - scopus: 2-s2.0-85054826264 (23)

2108/314344 - 2016 - Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Amelio, Ivano; Antonioli, Manuela; Aquilano, Katia; Bernassola, Francesca; Bordi, Matteo; Campanella, Michelangelo; Campello, Silvia; Cecconi, Francesco; Cianfanelli, Valentina; Ciriolo, Maria Rosa; Corazzari, Marco; De Zio, Daniela; Di Bartolomeo, Sabrina; Di Daniele, Nicola; Federici, Massimo; Filomeni, Giuseppe; Sanchez Hernandez, Luis Carlos; Lettieri Barbato, Daniele; Marfe', Gabriella; Melino, Sonia; Menghini, Rossella; Palumbo, Camilla; Piacentini, Mauro; Radogna, Flavia; Schiavi, Alfonso; Ventura, Natascia; Viscomi, Maria Teresa; Wang, Jing; Li, Yunxia; Zhang, Lilin - 01 - Articolo su rivista
paper: AUTOPHAGY (Philadelphia PA: Taylor & Francis Group LLC Georgetown TX: Landes Bioscience) pp. 1-222 - issn: 1554-8635 - wos: WOS:000373595400001 (3727) - scopus: 2-s2.0-85013763791 (4368)

2108/240132 - 2015 - Maintaining epithelial stemness with p63
Melino, Gennaro; Memmi, Elisa Maria; Bernassola, Francesca - 01 - Articolo su rivista
paper: SCIENCE SIGNALING () pp. re9- - issn: 1937-9145 - wos: WOS:000358594000003 (106) - scopus: 2-s2.0-84938344817 (104)

2108/132353 - 2015 - p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling
Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 3499-3504 - issn: 0027-8424 - wos: WOS:000351060000089 (137) - scopus: 2-s2.0-84925324776 (143)

2108/113677 - 2014 - High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy
Amelio, Ivano; Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. e1203- - issn: 2041-4889 - wos: WOS:000337229300003 (103) - scopus: 2-s2.0-84901048406 (107)

2108/113670 - 2014 - How the TP53 Family Proteins TP63 and TP73 contribute to tumorigenesis: Regulators and effectors
Candi, Eleonora; Agostini, Massimiliano; Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista
paper: HUMAN MUTATION (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 702-714 - issn: 1059-7794 - wos: WOS:000336618900007 (115) - scopus: 2-s2.0-84901244771 (121)

2108/113680 - 2014 - TAp73 promotes anabolism
Amelio, Ivano; Catani, Maria Valeria; Massoud, Renato; Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 12820-934- - issn: 1949-2553 - wos: WOS:000348038000024 (38) - scopus: 2-s2.0-84921340827 (39)

2108/93029 - 2014 - Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities.
Melino, Sonia; Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 7988-8013 - issn: 1949-2553 - wos: WOS:000348030900005 (81) - scopus: 2-s2.0-84907831745 (82)

2108/102752 - 2013 - Caspase-1 is a novel target of p63 in tumor suppression
Bernassola, Francesca; Melino, Gennaro; Amelio, Ivano - 01 - Articolo su rivista
paper: CELL DEATH & DISEASE (Nature Group) pp. e645-e645 - issn: 2041-4889 - wos: WOS:000319824100034 (44) - scopus: 2-s2.0-84879380549 (45)

2108/78434 - 2013 - The Cul4A-DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity
Melino, Gennaro; Bernassola, Francesca - 01 - Articolo su rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000325072200014 (21) - scopus: 2-s2.0-84884902595 (25)

2108/102782 - 2013 - p63 regulates glutaminase 2 expression
Bernassola, Francesca; Terrinoni, Alessandro; Agostini, Massimiliano; Melino, Gennaro - 01 - Articolo su rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 1395-1405 - issn: 1538-4101 - wos: WOS:000322758600014 (73) - scopus: 2-s2.0-84877127022 (76)

2108/78082 - 2012 - Guidelines for the use and interpretation of assays for monitoring autophagy
Bernassola, Francesca; Candi, Eleonora; Cecconi, Francesco; Ciriolo, Maria Rosa; De Felici, Massimo; Melino, Gennaro; Palumbo, Camilla; Piacentini, Mauro - 01 - Articolo su rivista
paper: AUTOPHAGY (Landes Bioscience Georgetown TX 78628) pp. 445-544 - issn: 1554-8627 - wos: WOS:000305403400002 (3357) - scopus: 2-s2.0-84862295360 (2923)

2108/16169 - 2010 - p63 and p73, the ancestors of p53.
Bernassola, Francesca; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista
paper: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (Woodbury, NY : Cold Spring Harbor Laboratory Press, c2009-) pp. - - issn: 1943-0264 - wos: WOS:000281575800013 (239) - scopus: 2-s2.0-78650873252 (274)

2108/16174 - 2010 - he E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 425-430 - issn: 0006-291X - wos: WOS:000284862300047 (33) - scopus: 2-s2.0-78149467848 (34)

2108/40290 - 2010 - NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2
Bernassola, Francesca; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 18061-18066 - issn: 0027-8424 - wos: WOS:000283184800041 (50) - scopus: 2-s2.0-78149271340 (55)

2108/40288 - 2010 - The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 425-430 - issn: 0006-291X - wos: WOS:000284862300047 (33) - scopus: 2-s2.0-78149467848 (34)

2108/40295 - 2010 - The ubiquitin proteasome system and its involvement in cell death pathways
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1-3 - issn: 1350-9047 - wos: WOS:000272818700001 (29) - scopus: 2-s2.0-77449132956 (28)

2108/16172 - 2010 - NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2
Bernassola, Francesca; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista
paper: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (National Academy of Sciences:2101 Constitution Avenue Northwest:Washington, DC 20418:(877)314-2253, (615)377-3322, EMAIL: subspnas@nas.edu, INTERNET: http://www.pnas.org, Fax: (615)377-0525) pp. 18061-18066 - issn: 0027-8424 - wos: WOS:000283184800041 (50) - scopus: 2-s2.0-78149271340 (55)

2108/40294 - 2010 - p63 and p73, the ancestors of p53
Bernassola, Francesca; Candi, Eleonora; Melino, Gennaro - 01 - Articolo su rivista
paper: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (Woodbury, NY : Cold Spring Harbor Laboratory Press, c2009-) pp. a004887- - issn: 1943-0264 - wos: WOS:000281575800013 (239) - scopus: 2-s2.0-78650873252 (274)

2108/38878 - 2009 - The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 3157-3166 - issn: 0950-9232 - wos: WOS:000269515100007 (79) - scopus: 2-s2.0-69849083542 (81)

2108/30419 - 2008 - Itch: A HECT-type E3 ligase regulating immunity, skin and cancer
Melino, Gennaro; Rossi, Mariacristina; Bernassola, Francesca - 01 - Articolo su rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1103-1112 - issn: 1350-9047 - wos: WOS:000256722700005 (143) - scopus: 2-s2.0-45449094801 (146)

2108/38297 - 2008 - Modelling and molecular dynamics of the interaction between the E3 ubiquitin ligase itch and the E2 UbcH7
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 1620-1627 - issn: 0006-2952 - wos: WOS:000261569400031 (15) - scopus: 2-s2.0-56149122833 (16)

2108/38295 - 2008 - The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: CANCER CELL (Cell Press) pp. 10-21 - issn: 1535-6108 - wos: WOS:000257655100005 (437) - scopus: 2-s2.0-45849153870 (453)

2108/34650 - 2006 - A cytoplasmic PML mutant inhibits p53 function
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 2688-2692 - issn: 1538-4101 - wos: WOS:000242897600022 (24) - scopus: 2-s2.0-33751211830 (22)

2108/34652 - 2006 - Cytoplasmic function of mutant promyelocytic leukemia (PML) and PML-retinoic acid receptor-α
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 14465-14473 - issn: 0021-9258 - wos: WOS:000207179300005 (31) - scopus: 2-s2.0-33744943554 (35)

2108/32393 - 2005 - The promyelocytic leukaemia protein tumour suppressor functions as a transcriptional regulator of p63
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 6982-6986 - issn: 0950-9232 - wos: WOS:000232701700013 (39) - scopus: 2-s2.0-27144507300 (40)

2108/29862 - 2004 - Ubiquitin-dependent degradation of p73 is inhibited by PML
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: JOURNAL OF EXPERIMENTAL MEDICINE (Rockefeller University Press:1114 First Avenue, Fourth Floor:New York, NY 10021:(212)327-8572, EMAIL: rupcd@rockvax.rockefeller.edu, INTERNET: http://www.rockefeller.edu/rupress, Fax: (212)327-7944) pp. 1545-1557 - issn: 0022-1007 - wos: WOS:000222047800010 (103) - scopus: 2-s2.0-2942657482 (108)

2108/50079 - 2002 - Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient
Bernassola, Francesca; Federici, Massimo; Corazzari, Marco; Terrinoni, Alessandro; Hribal, Marta Letizia; Ranalli, Marco; Barbetti, Fabrizio; Melino, Gennaro - 01 - Articolo su rivista
paper: THE FASEB JOURNAL (Federation of American Societies for Experimental Biology (FASEB):9650 Rockville Pike, Room L-2310:Bethesda, MD 20814:(800)433-2732, (301)530-7027, EMAIL: staff@dues.faseb.org, INTERNET: http://www.faseb.org, Fax: (301)571-5728, (301)530-7001) pp. 1371-1378 - issn: 0892-6638 - wos: WOS:000178441800011 (94) - scopus: 2-s2.0-0036720319 (102)

2108/50087 - 2002 - Osmotic resistance of high-density erythrocytes in transglutaminase 2-deficient mice
Bernassola, Francesca; Corazzari, Marco; Melino, Gennaro - 01 - Articolo su rivista
paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 1123-1127 - issn: 0006-291X - wos: WOS:000174466300003 (11) - scopus: 2-s2.0-0036298687 (13)

2108/50082 - 2002 - 'Tissue' transglutaminase ablation reduces neuronal death and prolongs survival in a mouse model of Huntington's disease
Bernassola, Francesca; Melino, Gennaro; Oliverio, Serafina; Piacentini, Mauro - 01 - Articolo su rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 873-880 - issn: 1350-9047 - wos: WOS:000177583300003 (191) - scopus: 2-s2.0-0036715380 (214)

2108/19321 - 2002 - GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma
Oliverio, Serafina; Ranalli, Marco; Corazzari, Marco; Rodolfo, Carlo; Bernassola, Francesca; Maccarrone, Mauro; Melino, Gennaro; Piacentini, Mauro - 01 - Articolo su rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 5158-5167 - issn: 0008-5472 - wos: WOS:000178066400009 (79) - scopus: 2-s2.0-0037105654 (80)

2108/16110 - 2001 - Inactivation of multiple targets by nitric oxide in CD95-triggered apoptosis.
Bernassola, Francesca; Catani, Maria Valeria; Corazzari, Marco; Rossi, Antonello; Melino, Gennaro - 01 - Articolo su rivista
paper: JOURNAL OF CELLULAR BIOCHEMISTRY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 123-133 - issn: 0730-2312 - wos: WOS:000169049400012 (13) - scopus: 2-s2.0-0034991311 (14)

2108/50094 - 2001 - Inactivation of multiple targets by nitric oxide in CD95-triggered apoptosis
Bernassola, Francesca; Catani, Maria Valeria; Corazzari, Marco; Rossi, Antonello; Melino, Gennaro - 01 - Articolo su rivista
paper: JOURNAL OF CELLULAR BIOCHEMISTRY (John Wiley & Sons Incorporated:Customer Service, 111 River Street:Hoboken, NJ 07030:(800)225-5945, (201)748-6000, EMAIL: societyinfo@wiley.com, INTERNET: http://www.wiley.com, Fax: (212)748-6551) pp. 123-133 - issn: 0730-2312 - wos: WOS:000169049400012 (13) - scopus: 2-s2.0-0034991311 (14)

2108/50090 - 2001 - The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. 4305-4316 - issn: 0950-9232 - wos: WOS:000169912600004 (203) - scopus: 2-s2.0-0035913190 (230)

2108/50088 - 2001 - Apoptosis in neuroblastomas induced by interferon-gamma involves the CD95/CD95L pathway
Bernassola, Francesca; Melino, Gennaro - 02 - Intervento a convegno
conference: Advances in Neuroblastoma Research Meeting (BATH, ENGLAND)
book: MEDICAL AND PEDIATRIC ONCOLOGY - ()

2108/89456 - 2000 - Nitric oxide can inhibit apoptosis or switch it into necrosis
Melino, Gennaro; Catani, Maria Valeria; Corazzari, Marco; Bernassola, Francesca - 01 - Articolo su rivista
paper: CELLULAR AND MOLECULAR LIFE SCIENCES (Birkhaeuser Verlag AG:Viaduktstrasse 42-44, CH 4051 Basel Switzerland:011 41 61 2050707, EMAIL: subscriptions@birkhauser.ch, INTERNET: http://www.birkhauser.ch, Fax: 011 41 61 2050792) pp. - - issn: 1420-682X - wos: WOS:000087342600011 (71) - scopus: 2-s2.0-0034021333 (81)

2108/50089 - 2000 - Distinct properties of fenretinide and CD437 lead to synergistic responses with chemotherapeutic reagents
Ranalli, Marco; Bernassola, Francesca; Piacentini, Mauro; Melino, Gennaro - 02 - Intervento a convegno
conference: Conference on Advances in Neuroblastoma Research (PHILADELPHIA, PENNSYLVANIA)
book: Medical and Pediatric Oncology - ()

2108/50093 - 2000 - Effector mechanisms of fenretinide-induced apoptosis in neuroblastoma
Ranalli, Marco; Bernassola, Francesca; Piacentini, Mauro; Melino, Gennaro - 01 - Articolo su rivista
paper: EXPERIMENTAL CELL RESEARCH (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 50-60 - issn: 0014-4827 - wos: WOS:000089791900006 (88) - scopus: 2-s2.0-0034633959 (90)

2108/41631 - 2000 - Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs
Ranalli, Marco; Bernassola, Francesca; Piacentini, Mauro; Melino, Gennaro - 01 - Articolo su rivista
paper: INTERNATIONAL JOURNAL OF CANCER (Hoboken N.J.: Wiley New York NY: Wiley-Liss) pp. 977-985 - issn: 0020-7136 - wos: WOS:000165619300022 (57) - scopus: 2-s2.0-0034672187 (64)

2108/89453 - 2000 - Nitric oxide inhibits cornified envelope formation in human keratinocytes by inactivating transglutaminases and activating protein 1
Rossi, Antonello; Catani, Maria Valeria; Candi, Eleonora; Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: JOURNAL OF INVESTIGATIVE DERMATOLOGY (Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680) pp. - - issn: 0022-202X - wos: WOS:000089816700023 (38) - scopus: 2-s2.0-0033770237 (38)

2108/89454 - 2000 - Nitric oxide inhibits apoptosis via AP-1-dependent CD95L transactivation
Melino, Gennaro; Bernassola, Francesca; Catani, Maria Valeria; Rossi, Antonello; Corazzari, Marco - 01 - Articolo su rivista
paper: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. - - issn: 0008-5472 - wos: WOS:000086862100014 (43) - scopus: 2-s2.0-0034194327 (47)

2108/50083 - 1999 - Regulation of transglutaminases by nitric oxide
Bernassola, Francesca; Rossi, Antonello; Melino, Gennaro - 02 - Intervento a convegno
conference: 2nd Annual Conference on Mechanisms of Cell Death (NEW YORK, NEW YORK)
book: MECHANISMS OF CELL DEATH - THE SECOND ANNUAL CONFERENCE OF THE CELL DEATH SOCIETY - (1-57331-240-1)

2108/50085 - 1999 - Induction of apoptosis by IFN gamma in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit
Bernassola, Francesca; Melino, Gennaro - 01 - Articolo su rivista
paper: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 652-660 - issn: 1350-9047 - wos: WOS:000081514800009 (38) - scopus: (0)

2108/50092 - 1998 - Inhibition of clotting factor XIII activity by nitric oxide
Catani, Maria Valeria; Bernassola, Francesca; Rossi, Antonello; Melino, Gennaro - 01 - Articolo su rivista
paper: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (San Diego [etc.]: Elsevier [etc.]) pp. 275-278 - issn: 0006-291X - wos: WOS:000075363000052 (66) - scopus: 2-s2.0-0032504540 (68)

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