PhD in NEUROSCIENCE

email: marina.diomedi@uniroma2.it
phone: 3386917110

CURRENT POSITION
Head of the Cerebrovascular Disease Center and Neurosonology Laboratory, Tor Vergata University Hospital, Rome.
Director of the UOSD Stroke Unit, Tor Vergata University Hospital of Rome. The stroke unit has obtained and maintained the UNI EN ISO 9001 Quality Certificate since April 2014
Member of the Regional Coordination of the Stroke Network at the Regional Directorate of Health and Social Policies, Lazio Region (det G03468 03/21/2018)
Associate Professor of Neurology (MED/26), – Department of Systems Medicine, University of Rome Tor Vergata

EDUCATION AND TRAINING
1991: Graduation in Medicine at the University of Rome Tor Vergata (110/110 cum laude).
1991-1995: Neurology Resident at the University of Rome Tor Vergata (50/50).
1995-1998: PhD in Neuropsychopathology of learning processes in the developmental age, University "Federico II", Naples.
1999: Scholarship for research activity on the theme "study of cerebral hemodynamics" at the I.R.C.C.S. S. Lucia Clinic, Rome
1999: Assistant Professor of Neurology (MED/26), University of Rome Tor Vergata, Rome
Since 9/6/14: National scientific qualification as Associate Professor scientific disciplinary sector 06/N1 (validity 09/06/2020)
Since 1/12/14: National scientific qualification as Associate Professor scientific disciplinary sector 06/D6 (validity 01/12/2020)
2018: II Level Master Degree in Health Economics and Management - Department of Economics and Finance
2021: Certificate of Management Training for Director in charge of a complex structure (D.G.R. 520/2019)
2019: Member of Board of Professors; Doctorate in Neuroscience, University of Rome Tor Vergata

WORK EXPERIENCE
Nov 1999: Researcher (06-D6 - MED26), Faculty of Medicine and Surgery, University of Rome Tor Vergata
Nov 1999 -Nov 2002 Assistant Professor at the Neurology Division of the S. Eugenio Hospital – Local Health Authority Rm/C of Rome
November 2002 Assistant Professor, Department of Neuroscience - Discipline of Neurology, Tor Vergata General Hospital
Head of the UOS "Cerebrovascular Diseases Study Center" and Neurosonology Laboratory, UOC Stroke Unit, Department of Neurosciences - Fondazione Policlinico Tor Vergata, Rome
Since 2011 National referent for the "Italian Neurosonological Certification in intensive care unit" in agreement with the National Transplant Center
10-May 2016 PhD Commission - Experimental Medicine XXIX cycle - University of L'Aquila
Nov 2016 -May 2018 Director UOC Neurovascular Treatment Unit (UTN), Tor Vergata University Hospital, Rome
Since May 2018 Head of the UOSD Stroke Unit, Tor Vergata University Hospital, Rome
Director for the II Level Master in "Management of acute stroke" (2018/2019)
Since March 2018 Member of the "Regional Coordination of the Stroke Network" at the Regional Directorate of Health and Social Policies, Lazio Region (det G03468 21/03/2018)
2019 Member of the Editorial Board of the European Journal of Neurology and Review Editor for Stroke Frontiers in Neurology
2018 Member of the Academic Board; PhD in Neuroscience, University of Rome Tor Vergata
November 2022 Associate Professor MED/26, in Neurology - Department of Systems Medicine, University of Rome Tor Vergata, Rome
Member of the Executive Committee of the European Society of Neurosonology and Cerebral Hemodynamics (ESNCH), Fellow member of the ESO, Member of the ISO.

Research Activities
The research activity is mainly focused on acute stroke recanalization therapies, stroke prevention and cerebral hemodynamics.
The main research fields include:
- Study of cerebral hemodynamics in various physiological and pathological conditions
- Efficacy and safety of recanalization therapies in acute ischemic stroke
- Efficacy and safety of secondary prevention therapies for ischemic stroke
Research activity in collaboration with international centers (Université de Lille, France; The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia)
Research and training activities in the European Stroke Organization and Italian Stroke Organization

TEACHING ACTIVITIES
Teaching: Degree Course Psychiatric Rehabilitation Techniques, Degree Course in Speech Therapy, Degree Course in Neurophysiopathology Technician, Degree Course in Cardiocirculatory Pathophysiology Techniques and Cardiovascular Perfusion, in the course of "Cerebrovascular Diseases" at the Postgraduate Schools of Neurology. In the course of Neurology at the Postgraduate Schools of Radiodiagnostics.
2013-2014 and 2014-2015: Organization of the II level Master in "Emergency Neurology", University of Rome Tor Vergata (1st and 2nd cycle).
2018/2019: Director of the II Level Master in "Management of acute stroke" University of Rome Tor Vergata

Recent courses:
1 December 2022 Scientific Director ECM Course "Update in the management of critically ill patients in the DEA", University of Rome Tor Vergata
5 May 2023 Postgraduate course in integrated clinical ultrasound for the intensivist: from medical-surgical emergencies to intensive care units AA 2022-2023, Catholic University of the Sacred Heart of Rome
May 17, 2023 Scientific Director ECM Course "STROKE IN EMERGENCY: NEWS BETWEEN GUIDELINES AND OPERATIONAL PATHS". Tor Vergata University Hospital, Rome
9-11 May 2023 3rd National Congress S.I.Me.Ge.N. "Medical therapy of cerebral hemorrhage", Rome
14-15 June 2023 Upgrade in Donation and Transplantation. “Evolution of brain injury towards brain death“, Tor Vergata University Hospital, Rome
16-23 June 2023 SUMMER SCHOOL ISA: Brain Hemorrhage. "The resumption of antiplatelet or anticoagulant therapy in the patient after a cerebral hemorrhage", Rome

Memberships:
- 2008-2016 Executive Committee Member of the "Italian Society of Neurosonology and Cerebral Hemodynamics" (SINSEC)
- 2013-2019 Past Executive Committee Member of the European Society of Neurosonology and Cerebral Hemodynamics (ESNCH)
- Fellow Member of the European Stroke Organization (FESO)
- Member of the World Stroke Association (WSA)
- Società Italiana di Neurologia (SIN)
- Italian Stroke Association (ISA)
- Professional Member of the American Heart Association & American Stroke Association

Clinical Studies
• 2005 PERFORM (Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischaemic strOke or tRansient ischeMic attack)
• 2006 AIFA “Pharmaco epidemiological studies aimed at defining the benefit-risk profile of treatments and the impact of strategies for improving the appropriateness of drug use. Topic: Studies on pharmacological treatments of chronic headache”.
• 2006 PRIN “Neuro Marker infiammatori nel TIA (INITIA): potenziale valore predittivo sull’outcome.” (prot. 2006060914)
• 2007: Grant Markers infiammatori nel paziente con TIA: potenziale valore predittivo sull’outcome
• 2010: Insulin Resistance Intervention after Stroke (IRIS) Trial [5 U01 NS 044876-04], supported by the National Institute of Neurological Disorders and Stroke (NINDS)
• 2013: Italian Ministry of Health The prognostic value of collateral flow in acute ischemic stroke secondary to occlusion of intracranial arteries treated by endovascular therapy
• 2015: PI Bayer 56-7939/16573 - Multicenter, randomized, double-blind, double-dummy, active-comparator, event-driven, superiority phase III study of secondary prevention of stroke and prevention of systemic embolism in patients with a recent
Embolic Stroke of Undetermined Source (ESUS), comparing rivaroxaban 15 mg once daily with aspirin 100 mg (NAVIGATE ESUS)
• 2017: “Non-interventional study on Edoxaban Treatment in routiNe clinical prActice for patients with non valvular Atrial Fibrillation (ETNA-AF-Europe)” Prot. N° DSE-EDO-04-14-EU
• 2018: Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction (CHARM)
• 2018: I-NIC “Studio multicentrico prospettico randomizzato controllato con placebo e in doppio cieco per valutare l’efficacia dei campi elettromagnetici usati a bassa frequenza (ELF-MF) in pazienti affetti da ischemia cerebrale in fase acuta
• 2018: A phase 4 Randomized Clinical Trial of Andexanet Alfa in Acute Intracranial Hemorrhage in Patients Receiving an Oral Factor Xa Inhibitor. EudraCT: 2018-002620-17
• 2021-2023 Network Program WP1 Lazio: Effectiveness of audit and feedback interventions to improve the quality of care and reduce inequalities of access to effective care in different clinical and organizational contexts.
• 2023 Phase 3 study to investigate the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) compared with placebo in participants after an acute noncardioembolic ischemic stroke or high-risk TIA
• European Funding 2023: MNESYS A multiscale integrated approach to the study of the nervous system in health and disease