DANIELA BARILA'

Professore ordinario

email: daniela.barila@uniroma2.it
telefono: 06 7259 4326
edificio: SOGENE
stanza: 326

Istruzione e formazione

2000-2001: “Assegno di Ricerca”, Dipartimento di Medicina Sperimentale e Scienze Biochimiche, Università “Tor Vergata”, Roma.

1995-1999: Borsista post-doc presso il laboratorio diretto dal Prof. G. Superti-Furga, European Molecular Biology Laboratory (E.M.B.L.), Heidelberg, DE.

1994: Specializzazione in Biotecnologie, Università “La Sapienza”, Roma, IT.

1993: Borsista ospite presso il laboratorio diretto dal Prof. Takashi Morimoto, Dipartimento di “Cell Biology”, New York University, NYU, New York, USA.

1991 Laurea in Scienze Biologiche, Università "La Sapienza", Roma, IT.

1989-1994: Studente Tirocinante laureando e poi studente specializzando in Biotecnologie, presso l’Unità di Nutrizione Sperimentale, INRAN, sotto la guida della Dr. G. Perozzi e Prof. I . Bozzoni.

Impiego ed Incarichi di Ricerca

2023- presente: Professore Ordinario presso il Dipartimento di Biologia Università “Tor Vergata”, Roma, SSD BIO/18 (Genetica).

2018-presente: Professore Associato presso il Dipartimento di Biologia Università “Tor Vergata”, Roma, SSD BIO/18 (Genetica).

2008-2018: Ricercatore Universitario Confermato presso il Dipartimento di Biologia Università “Tor Vergata”, Roma, SSD BIO/18 (Genetica).

2006-presente: Responsabile del Laboratorio di Trasduzione del Segnale, presso il CERC, Fondazione Santa Lucia, Roma.

2001-2007: Assistant Telethon Scientist, Dulbecco Telethon Institute presso il Dipartimento di Medicina Sperimentale e Scienze Biochimiche, Università “Tor Vergata”, Roma.

Insegnamenti

Docente Titolare Corso “Genetica della Trasformazione Neoplastica” (6CFU, BIO/18), Laurea Magistrale in Biologia Cellulare e Molecolare e Scienze Biomediche, Università “Tor Vergata”.

Docente Titolare Corso “Gene Expression and Regulation” (6CFU, BIO/18), Master of Science (Laurea Magistrale) in Biotechnology, Università “Tor Vergata”.

Docente Titolare Corso “Experimental approaches to study neoplastic transformtion” (3CFU), The Master of Science in Biotechnology, Università “Tor Vergata”.

Docente Titolare Corso “Modelli Sperimentali per lo studio della Biologia Cellulare Molecolare”, Corso di dottorato in Biologia Cellulare e Molecolare, Dip. Biologia, Università “Tor Vergata”.

Interessi di Ricerca

Studio delle vie di segnalazione innescate da tirosine chinasi recettoriali (come EGFR, MET e HER2), tirosin chinasi non recettoriali (come ABL e SRC) e chinasi coinvolte nella risposta al danno del DNA (come ATM) in modelli cellulari di glioblastoma e cancro al seno per capire come gli oncogeni. “dirottano” la segnalazione cellulare per sostenere l'inizio e lo sviluppo del cancro e la resistenza a terapia. Abbiamo scoperto e stiamo attualmente lavorando su diverse nuove interazioni molecolari:

- Interazione tra chinasi SRC e Caspasi-8 che consente alle cellule tumorali di dirottare l'attività di Caspasi-8 compromettendo la sua funzione apoptotica canonica e attivando la sua capacità di promuovere l'angiogenesi e il microambiente tumorale.

- Interazione HER2_ATM che consente all'attività della chinasi ATM di sostenere l'attività di HSP90 e l'interazione con HER2 promuovendone la tumorigenicità.

- Ruolo di Caspase-8 nella riparazione del danno al DNA e nella resistenza alla radio-chemioterapia.

- Identificazione di un nuovo ruolo della chinasi Src come modulatore dell'attività del fattore di trascrizione NRF2 e della resistenza alla ferroptosi.

Produzione scientifica

2108/344683 - 2024 - NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

Cirotti, Claudia; Taddei, Irene; Contadini, Claudia; Di Girolamo, Claudia; Pepe, Gerardo; De Bardi, Marco; Helmer Citterich, Manuela; Barila', Daniela - 01 - Articolo su rivista

rivista: LIFE SCIENCE ALLIANCE ([Woodbury NY]: Life Science Alliance LLC, [2018]-) pp. - - issn: 2575-1077 - wos: WOS:001112691200011 (4) - scopus: 2-s2.0-85175218482 (4)

2108/332603 - 2023 - Caspase-8 and Tyrosine Kinases: A Dangerous Liaison in Cancer

Cirotti, Claudia; Barila', Daniela - 01 - Articolo su rivista

rivista: CANCERS (Basel: MDPI) pp. 3271- - issn: 2072-6694 - wos: WOS:001033274900001 (3) - scopus: 2-s2.0-85164910384 (4)

2108/332207 - 2023 - A Triphenylphosphonium-Functionalized Delivery System for an ATM Kinase Inhibitor That Ameliorates Doxorubicin Resistance in Breast Carcinoma Mammospheres

Barila', Daniela - 01 - Articolo su rivista

rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000948225800001 (3) - scopus: 2-s2.0-85149864575 (3)

2108/309616 - 2023 - Caspase-8 as a novel mediator linking Src kinase signaling to enhanced glioblastoma malignancy

Cirotti, Claudia; Sacco, Francesca; Volpe, Elisabetta; Barila', Daniela - 01 - Articolo su rivista

rivista: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 417-428 - issn: 1350-9047 - wos: WOS:000912614200001 (8) - scopus: 2-s2.0-85143211440 (8)

2108/349465 - 2023 - Identification and Biological Characterization of the Pyrazolo[3,4-d]pyrimidine Derivative SI388 Active as Src Inhibitor

Contadini, Claudia; Cirotti, Claudia; Norouzi, Mehrdad; Barila', Daniela; Musumeci, Francesca - 01 - Articolo su rivista

rivista: PHARMACEUTICALS (Basel : MDPI, Molecular Diversity Preservation International, 2004-) pp. - - issn: 1424-8247 - wos: WOS:001037616100001 (2) - scopus: 2-s2.0-85166271315 (2)

2108/349464 - 2023 - Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species

Schiavi, Alfonso; Cirotti, Claudia; Maglioni, Silvia; Barila', Daniela; Ventura, Natascia - 01 - Articolo su rivista

rivista: CELL DEATH DISCOVERY ([London]: Nature Publishing Group, 2015-) pp. - - issn: 2058-7716 - wos: WOS:001083952600001 (6) - scopus: 2-s2.0-85174268426 (6)

2108/308415 - 2022 - DNA Damage Regulates the Functions of the RNA Binding Protein Sam68 through ATM-Dependent Phosphorylation

Barila', Daniela; Bielli, Pamela; Sette, Claudio - 01 - Articolo su rivista

rivista: CANCERS (Basel: MDPI) pp. 3847- - issn: 2072-6694 - wos: WOS:000847191300001 (5) - scopus: 2-s2.0-85137347082 (5)

2108/262413 - 2021 - Redox activation of ATM enhances GSNOR translation to sustain mitophagy and tolerance to oxidative stress

Cirotti, Claudia; Rizza, Salvatore; Giglio, Paola; Poerio, Noemi; Barila', Daniela; Cecconi, Francesco; Fraziano, Maurizio; Filomeni, Giuseppe - 01 - Articolo su rivista

rivista: EMBO REPORTS () pp. - - issn: 1469-3178 - wos: WOS:000592496700001 (33) - scopus: 2-s2.0-85096775997 (36)

2108/279773 - 2021 - Guidelines for the use and interpretation of assays for monitoring autophagy. 4th edition

Barila', Daniela; Bei, Roberto; Bordi, Matteo; Campello, Silvia; Cecconi, Francesco; Colasuonno, Fiorella; Di Sano, Federica; Filomeni, Giuseppe; Nazio, Francesca; Palumbo, Camilla - 01 - Articolo su rivista

rivista: AUTOPHAGY (Philadelphia PA: Taylor & Francis Group LLC Georgetown TX: Landes Bioscience) pp. 1-382 - issn: 1554-8635 - wos: WOS:000636121800001 (946) - scopus: 2-s2.0-85102619204 (1554)

2108/284845 - 2021 - ATM Kinase-Dependent Regulation of Autophagy: A Key Player in Senescence?

Cirotti, Claudia; Barila', Daniela - 01 - Articolo su rivista

rivista: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (Lausanne : Frontiers Media S.A., 2013-) pp. 599048- - issn: 2296-634X - wos: WOS:000609121800001 (36) - scopus: 2-s2.0-85099731680 (39)

2108/258219 - 2020 - mTOR inhibition leads to SRC-mediated EGFR internalisation and degradation in glioma cells

Fuoco, Claudia; Barila', Daniela; Di Bartolomeo, Sabrina - 01 - Articolo su rivista

rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000579605500001 (8) - scopus: 2-s2.0-85089591993 (9)

2108/258228 - 2020 - Targeting the DNA damage response to overcome cancer drug resistance in glioblastoma

Barila', Daniela - 01 - Articolo su rivista

rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. - - issn: 1661-6596 - wos: WOS:000554257700001 (44) - scopus: 2-s2.0-85087795139 (48)

2108/258610 - 2020 - SRC kinase in glioblastoma: news from an old acquaintance

Cirotti, Claudia; Barila', Daniela - 01 - Articolo su rivista

rivista: CANCERS (Basel: MDPI) pp. - - issn: 2072-6694 - wos: WOS:000549308400001 (33) - scopus: 2-s2.0-85086439593 (36)

2108/228285 - 2019 - Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation

Mongiardi, Maria Patrizia; Pacioni, Simone; Del Re, Andrea; Barila', Daniela - 01 - Articolo su rivista

rivista: ONCOGENE (Basingstoke: Nature Publishing Group.) pp. 5413-5424 - issn: 1476-5594 - wos: WOS:000473842500006 (32) - scopus: 2-s2.0-85064081474 (36)

2108/211987 - 2018 - Caspase-8: A novel target to overcome resistance to chemotherapy in glioblastoma

Fianco, Giulia; Cirotti, Claudia; Barila', Daniela - 01 - Articolo su rivista

rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel (Matthaeustrasse 11) : Molecular Diversity Preservation International MDPI) pp. 3798- - issn: 1661-6596 - wos: WOS:000455323500100 (43) - scopus: 2-s2.0-85057972427 (43)

2108/211979 - 2018 - Ataxia-telangiectasia mutated kinase in the control of oxidative stress, mitochondria, and autophagy in cancer: A maestro with a large orchestra

Cirotti, Claudia; Barila', Daniela - 01 - Articolo su rivista

rivista: FRONTIERS IN ONCOLOGY (Lausanne : Frontiers Editorial Office, 2011-) pp. 73- - issn: 2234-943X - wos: WOS:000427588100001 (42) - scopus: 2-s2.0-85044384170 (42)

2108/207950 - 2017 - ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

Antonelli, Martina; Sambucci, Manolo; Vitale, Ilio; Barila', Daniela - 01 - Articolo su rivista

rivista: ONCOTARGET (Albany, N.Y. : Impact Journals) pp. 21692-21709- - issn: 1949-2553 - wos: WOS:000397642400097 (35) - scopus: 2-s2.0-85016411430 (39)

2108/185017 - 2017 - Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma

Fianco, Giulia; Gentile, Antonietta; Centonze, Diego; Barila', Daniela - 01 - Articolo su rivista

rivista: ELIFE (Cambridge: eLife Sciences Publications) pp. 1-16 - issn: 2050-084X - wos: WOS:000402874100001 (50) - scopus: 2-s2.0-85023596687 (51)

2108/173573 - 2016 - Caspase-8 expression and its Src-dependent phosphorylation on Tyr380 promote cancer cell neoplastic transformation and resistance to anoikis

Fianco, Giulia; Barila', Daniela - 01 - Articolo su rivista

rivista: EXPERIMENTAL CELL RESEARCH (Academic Press Incorporated:6277 Sea Harbor Drive:Orlando, FL 32887:(800)543-9534, (407)345-4100, EMAIL: ap@acad.com, INTERNET: http://www.idealibrary.com, Fax: (407)352-3445) pp. 114-122 - issn: 0014-4827 - wos: WOS:000383217500012 (20) - scopus: 2-s2.0-84995543438 (20)

2108/211975 - 2016 - ATM: An unexpected tumor-promoting factor in HER2-expressing tumors

Oropallo, Veronica; Barila', Daniela - 01 - Articolo su rivista

rivista: MOLECULAR & CELLULAR ONCOLOGY (Austin, TX : Landes Bioscience) pp. e1054551- - issn: 2372-3556 - wos: WOS:000385247100014 (2) - scopus: 2-s2.0-85044392731 (2)

2108/113495 - 2015 - FAS-ligand regulates differential activation-induced cell death of human T-helper 1 and 17 cells in healthy donors and multiple sclerosis patients

Cencioni, Maria Teresa; Centonze, Diego; Barila', Daniela; Volpe, Elisabetta - 01 - Articolo su rivista

rivista: CELL DEATH & DISEASE (Nature Group) pp. e1741- - issn: 2041-4889 - wos: WOS:000357513200006 (23) - scopus: 2-s2.0-84935070637 (31)

2108/115459 - 2015 - ATM kinase sustains HER2 tumorigenicity in breast cancer

Barila', Daniela - 01 - Articolo su rivista

rivista: NATURE COMMUNICATIONS (London: Nature Publishing Group-Springer Nature) pp. 6886- - issn: 2041-1723 - wos: WOS:000353703600008 (53) - scopus: 2-s2.0-84928041749 (57)

2108/115496 - 2014 - ITCH E3 ligase in ATM network

Barila', Daniela - 01 - Articolo su rivista

rivista: ONCOSCIENCE (Impact Journals LLC -) pp. 394-395 - issn: 2331-4737 - wos: (0) - scopus: 2-s2.0-84957940796 (4)

2108/79047 - 2014 - ATM kinase activity modulates ITCH E3-ubiquitin ligase activity

Pellegrini, Manuela; Barila', Daniela - 01 - Articolo su rivista

rivista: ONCOGENE (Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358) pp. - - issn: 0950-9232 - wos: WOS:000331933800005 (31) - scopus: 2-s2.0-84896702019 (31)

2108/87708 - 2014 - Tug of war between survival and death: exploring ATM function in cancer.

Barila', Daniela - 01 - Articolo su rivista

rivista: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Basel: MDPI Center) pp. 5388-5409 - issn: 1422-0067 - wos: WOS:000336841200014 (20) - scopus: 2-s2.0-84897372769 (23)

2108/115494 - 2013 - ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition

Barila', Daniela - 01 - Articolo su rivista

rivista: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (London : BioMed Central) pp. 95- - issn: 1756-9966 - wos: WOS:000329190800003 (82) - scopus: 2-s2.0-84887792084 (84)

2108/77542 - 2012 - Met acts through Abl to regulate p53 transcriptional outcomes and cell survival in the developing liver

Barila', Daniela - 01 - Articolo su rivista

rivista: JOURNAL OF HEPATOLOGY (Blackwell Munksgaard:PO Box 2148, Periodicals Department, DK-1016 Copenhagen K Denmark:011 45 33 755913, EMAIL: agentservices@oxon.blackwellpublishing.com, INTERNET: http://www.blackwellmunksgaard.com, Fax: 011 45 77 333377) pp. 1292-1298 - issn: 0168-8278 - wos: WOS:000311771300020 (17) - scopus: 2-s2.0-84869231205 (17)

2108/77568 - 2012 - Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity

Barila', Daniela; Urbani, Andrea - 01 - Articolo su rivista

rivista: JOURNAL OF PROTEOMICS () pp. 4632-4646 - issn: 1874-3919 - wos: 000307609500008 (16) - scopus: 2-s2.0-84864083040 (17)

2108/102750 - 2012 - A new player in the development of TRAIL based therapies for hepatocarcinoma treatment: ATM kinase

Barila', Daniela - 01 - Articolo su rivista

rivista: CANCERS (Basel: MDPI) pp. 354-378 - issn: 2072-6694 - wos: (0) - scopus: 2-s2.0-84862648880 (5)

2108/102745 - 2012 - Molecular Bases of Ataxia Telangiectasia: One Kinase Multiple Functions

Barila', Daniela - 03 - Contributo in libro

libro: Genetic Disorders - ()

2108/10558 - 2011 - Abl interconnects oncogenic Met and p53 core pathways in cancer cells

Barila', Daniela - 01 - Articolo su rivista

rivista: CELL DEATH AND DIFFERENTIATION (Nature Publishing Group:Brunel Road Houndmills, Basingstoke RG21 6XS United Kingdom:011 44 20 78334000, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: 011 44 20 78434640) pp. 1608-1616 - issn: 1350-9047 - wos: WOS:000294757800008 (56) - scopus: 2-s2.0-80052693990 (62)

2108/79183 - 2011 - Oxygen sensing is impaired in ATM-defective cells

Barila', Daniela - 01 - Articolo su rivista

rivista: CELL CYCLE (Landes Bioscience, c2002, Georgetown, TX) pp. 4311-4320 - issn: 1538-4101 - wos: WOS:000298407200032 (14) - scopus: 2-s2.0-84055184840 (16)

2108/10550 - 2010 - ATM kinase activity modulates cFLIP protein levels: potential interplay between DNA damage signalling and TRAIL-induced apoptosis

Barila', Daniela - 01 - Articolo su rivista

rivista: CARCINOGENESIS (Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 1956-1963 - issn: 0143-3334 - wos: WOS:000283922400007 (29) - scopus: 2-s2.0-78149257662 (33)

2108/8001 - 2009 - Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis

Barila', Daniela - 01 - Articolo su rivista

rivista: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 3755-3763 - issn: 0008-5472 - wos: WOS:000265761900006 (114) - scopus: 2-s2.0-65949097277 (119)

2108/6406 - 2008 - Identification of a critical tyrosine residue in caspase 8 that promotes cell migration

Barila', Daniela - 01 - Articolo su rivista

rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 13031-13034 - issn: 0021-9258 - wos: WOS:000255499800040 (68) - scopus: http://www.scopus.com/inward/record.url?eid=2-s2.0-45149096045&partnerID=40&md5=6a1b98702bc738f3a88145e9cb34784f (0)

2108/8804 - 2008 - ATM Kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells

Condo', Ivano; Testi, Roberto; Barila', Daniela - 01 - Articolo su rivista

rivista: BLOOD (New York: Elsevier Inc. [Washington DC etc.]: American Society of Hematology) pp. 829-837 - issn: 0006-4971 - wos: WOS:000252458700057 (23) - scopus: 2-s2.0-38349087547 (24)

2108/7949 - 2008 - Caspase 8 promotes peripheral localization and activation of Rab5

Barila', Daniela - 01 - Articolo su rivista

rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 36280-36289 - issn: 0021-9258 - wos: WOS:000261840500024 (46) - scopus: http://www.scopus.com/inward/record.url?eid=2-s2.0-61349156806&partnerID=40&md5=94e0ec8ee81feb789d2c0686853d6a7b (0)

2108/6261 - 2007 - Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma

Barila', Daniela - 01 - Articolo su rivista

rivista: CANCER RESEARCH (American Association of Cancer Research:150 South Independence Mall West, #826:Philadelphia, PA 19106:(215)440-9300, EMAIL: pubs@aacr.org, INTERNET: http://www.aacr.org, Fax: (215)440-7228) pp. 1680-1688 - issn: 0008-5472 - wos: WOS:000244289200035 (58) - scopus: http://www.scopus.com/inward/record.url?eid=2-s2.0-33847710605&partnerID=40&md5=d214dc72f8b1f90a354e43cba6ca299a (0)

2108/10553 - 2006 - c-Abl acetylation by histone acetyltransferases regulates its nuclear-cytoplasmic localization

Testi, Roberto; Barila', Daniela - 01 - Articolo su rivista

rivista: EMBO REPORTS (Oxford : Oxford University Press, 2000-) pp. 727-733 - issn: 1469-221X - wos: WOS:000238687800017 (46) - scopus: 2-s2.0-33745594612 (47)

2108/10559 - 2006 - Deregulation of proteasome function induces Abl-mediated cell death by uncoupling p130CAS and c-CrkII

Barila', Daniela - 01 - Articolo su rivista

rivista: THE JOURNAL OF BIOLOGICAL CHEMISTRY (American Society for Biochemistry and Molecular Biology:9650 Rockville Pike:Bethesda, MD 20814:(301)530-7145, EMAIL: asbmb@asbmb.faseb.org, INTERNET: http://www.faseb.org/asbmb, Fax: (301)571-1824) pp. 2430-2440 - issn: 0021-9258 - wos: WOS:000234931800005 (21) - scopus: http://www.scopus.com/inward/record.url?eid=2-s2.0-33646343494&partnerID=40&md5=35b7a9074f84d486689762a006e00723 (0)

2108/8809 - 2006 - Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression

Rufini, Alessandra; Condo', Ivano; Testi, Roberto; Barila', Daniela - 01 - Articolo su rivista

rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 1895-1905 - issn: 0261-4189 - wos: WOS:000237589900010 (161) - scopus: 2-s2.0-33646542701 (170)

2108/8813 - 2003 - Caspase-dependent cleavage of c-Abl contributes to apoptosis

Barila', Daniela; Rufini, Alessandra; Condo', Ivano; Testi, Roberto - 01 - Articolo su rivista

rivista: MOLECULAR AND CELLULAR BIOLOGY (American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342) pp. 2790-2799 - issn: 0270-7306 - wos: WOS:000182049900014 (54) - scopus: 2-s2.0-0037383316 (59)

2108/10560 - 2002 - c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

Barila', Daniela - 01 - Articolo su rivista

rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 514-524 - issn: 0261-4189 - wos: WOS:000174014700004 (100) - scopus: 2-s2.0-0037084333 (114)

2108/10561 - 2000 - Nuclear tyrosine phosphorylation: the beginning of a map

Barila', Daniela - 01 - Articolo su rivista

rivista: BIOCHEMICAL PHARMACOLOGY (-Oxford, United Kingdom: Elsevier Science Limited -London ; New York : Pergamon Press, 1958-) pp. 1203-1215 - issn: 0006-2952 - wos: (0) - scopus: (0)

2108/9193 - 2000 - A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK

Barila', Daniela; Gonfloni, Stefania - 01 - Articolo su rivista

rivista: EMBO JOURNAL (attuale: NATURE PUBLISHING GROUP, 345 PARK AVENUE SOUTH, NEW YORK, USA, NY, 10010-1707 Precedente: Oxford University Press:Journals Department, Great Clarendon Street, Oxford OX2 6DP United Kingdom:011 44 1865 556767, EMAIL: jnlorders@oup.co.uk, INTERNET: http://www.oup.co.uk, Fax: 011 44 1865 267485) pp. 273-281 - issn: 0261-4189 - wos: WOS:000084961800012 (76) - scopus: 2-s2.0-0034677210 (79)

2108/10562 - 1999 - Regulation of human c-Abl tyrosine kinase activity in Xenopus oocytes and acceleration of progesterone-induced G2/M transition by oncogenic forms

Barila', Daniela - 01 - Articolo su rivista

rivista: BIOLOGICAL CHEMISTRY (Walter de Gruyter and Company:Genthinerstrasse 13, D 10785 Berlin Germany:011 49 30 260050, EMAIL: customerservice@deguyter.de, INTERNET: http://www.degruyter.de/, Fax: 011 49 30 26005338) pp. 223-230 - issn: 1431-6730 - wos: (0) - scopus: (0)

2108/10564 - 1998 - Effects of retinoids on gene expression in different epithelial models in vivo and in vitro

Barila', Daniela - 01 - Articolo su rivista

rivista: ZEITSCHRIFT FUR ERNAHRUNGSWISSENSCHAFT (Dr Dietrich Steinkopff Verlag:PO Box 111442, D-64229 Darmstadt Germany:011 49 6151 828990, EMAIL: scheffler.steinkopff@springer.de, INTERNET: http://www.steinkopff.springer.de, Fax: 011 49 6151 8289940) pp. 29-34 - issn: 0044-264X - wos: (0) - scopus: (0)

2108/10566 - 1998 - An intramolecular SH3-domain interaction regulates c-Abl activity

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rivista: NATURE GENETICS (Nature America Incorporated:345 Park Avenue South, 6th Floor:New York, NY 10010:(888)331-6288, EMAIL: institutions@natureny.com, INTERNET: http://www.nature.com, Fax: (212)689-9108) pp. 280-282 - issn: 1061-4036 - wos: WOS:000072325000029 (182) - scopus: 2-s2.0-0031882251 (189)

2108/10565 - 1996 - The Dri 42 gene, whose expression is up-regulated during epithelial differentiation, encodes a novel endoplasmic reticulum resident transmembrane protein

Barila', Daniela - 01 - Articolo su rivista

2108/10563 - 1995 - Transcriptional regulation of the ezrin gene during rat intestinal development and epithelial differentiation

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rivista: BIOCHIMICA ET BIOPHYSICA ACTA (Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598) pp. 133-140 - issn: 0006-3002 - wos: (0) - scopus: (0)

2108/10555 - 1994 - Subtractive hybridization cloning of novel genes differentially expressed during intestinal development

Barila', Daniela - 01 - Articolo su rivista

rivista: EUROPEAN JOURNAL OF BIOCHEMISTRY (Blackwell Science Limited:PO Box 88, Oxford OX2 0NE United Kingdom:011 44 1865 776868, 011 44 1865 206038, EMAIL: journals.cs@blacksci.co.uk, INTERNET: http://www.blackwell-science.com, Fax: 011 44 1865 721205) pp. 701-709 - issn: 0014-2956 - wos: WOS:000238687800017 (46) - scopus: http://www.scopus.com/inward/record.url?eid=2-s2.0-33745594612&partnerID=40&md5=b5f6e3600eb77c851b80ca5066ad23d1 (0)