Name: AMEDEO FERLOSIO
e-mail: ferlosio@med.uniroma2.it
pec: amedeo.ferlosio@omceoromapec.it
Nationality: Italian
Academic position:
associate professor med/08 Department of Biomedicine and Prevention, University of Rome Tor Vergata.
Healthcare position:
holder of the type B company program "pleuro-pulmonary and head and neck pathology", Tor Vergata Polyclinic in Rome.
PROFESSIONAL EXPERIENCE
2024 April 1: holder of the clinical program type B pleuro-pulmonary and head and neck pathology, Policlinico Tor Vergata.
2022 November: start of service as associate professor med/08 Department of Biomedicine and Prevention, University of Rome Tor Vergata.
2020-2024: member of the specialization school in Microbiology, University Tor Vergata of Rome.
2019: national scientific qualification as second level professor, competitive sector 06/A4 for the scientific disciplinary sector med/08.
29 November 2019: Speaker at the ECM Course “Diagnosis and management of patients with IPF: the Hub and Spoke model”, Rome, Italy.
13 December 2018: moderator at the ECM Course “Pathological Anatomy and focus on ALK, ROS1, RET and MET”, Rome, Italy.
September 2018: Speaker at the ECM course “Idiopathic Pulmonary Fibrosis”, Rome, Italy
September 29, 2017: Speaker at the ECM course “IPF: diagnostic challenge”, Rome, Italy.
2017 (January): appointed as quality management manager (RSGQ) of the UOC of Pathological Anatomy of the Policlinico di Roma “Tor Vergata”.
11-12 November 2016: speaker at the AIPO Lazio section meeting "a new pneumology". Rome, Italy.
23 September 2016: Speaker at the ECM course "IPF: the patient at the center", Rome, Italy.
September 2015 to date: professional assignment at the Policlinico di Roma “Tor Vergata”, UOSD Pathological Anatomy.
December 2015 to date: appointed as contact person for the Pathological Anatomy service of the Policlinico di Roma Tor Vergata in the context of the activities of the Lazio Region Tumor Registry.
2015 to date: participation in multidisciplinary meetings for the diagnostic and therapeutic classification of patients with interstitial lung diseases.
2015 to date: participation in multidisciplinary meetings for the diagnostic and therapeutic framework of patients with pulmonary nodules.
2015 to date: participation in multidisciplinary meetings of the oncology "WOG" of patients with pleuro-pulmonary tumors.
2013 to date: teaching of Pathological Anatomy of the Degree Course in Dentistry at the University "Our Lady of Good Counsel" of Tirana, Albania.
2012-to date. Appointed professor of the School of Specialization in Respiratory Diseases, University of Rome Tor Vergata.
2012-to date: Establishment of the Master's Degree Course in Dentistry and Dental Prosthetics.
2012-13: Establishment of the Degree Course in Nursing Sciences.
2012 to date: Assignment of the teaching of Pathological Anatomy for the Dental Hygiene Course, University of Rome Tor Vergata 2 CFU
2012- today: teaching module of Pathological Anatomy, 3rd year of Medicine and Surgery.
2012-14: Member of the commission for research doctorates, masters and advanced courses of the Italian College of Professors of Pathological Anatomy.
2011- today: associate professor in Pathological Anatomy for the Master's Degree in Dentistry and Dental Prosthetics, coordinator prof. GP Palmieri, teaching module of Pathological Anatomy (1+1 CFU), University of Rome Tor Vergata.
2011- to date: member of the examining committee for the oral exam of Pathological Anatomy of the Master's Degree in Dentistry and Dental Prosthetics, Faculty of Medicine and Surgery, University of Rome "Tor Vergata".
2010- 2011: on-call shifts for organ suitability, Transplant Agency of the Lazio region.
2010- to date: associate professor of Pathological Anatomy of the Degree in Medicine and Surgery, teaching module Practical Medicine in the third year (1 CFU).
2010-2015: consultant pathologist for third parties, Policlinico Casilino, Rome.
2008-2015: consultant pathologist for third parties, IRCCS San Raffaele Pisana, Rome.
2010-2015: consultant pathologist for third parties, Nuova Clinica Annunziatella, Rome.
2013-2015: consultant pathologist for third parties at the Neurological Center of Latium, Rome.
2010: appointed by the Lazio Regional Transplant Agency as a monitoring body for the research project approved by the CNR, entitled “Identification of prognostic factors and escape mechanisms of colorectal cancer: role of NK cells derived from hematopoietic stem cells”.
2010- to date: member of the teaching staff of the doctorate "ADVANCED TECHNOLOGIES IN BIOMEDICINE", University of Rome Tor Vergata.
2008- to date: teacher at the School of Specialization in Pathological Anatomy, University of Rome Tor Vergata.
2009- to date: member of the examining board for the oral exams in Pathological Anatomy at the Faculty of Medicine and Surgery.
2008 (1-October): Started as a researcher in Pathological Anatomy at the University of Rome Tor Vergata, Department of Biopathology and Diagnostic Imaging.
2008: Winner of the competition as a researcher in the disciplinary sector med/08 (Pathological Anatomy).
2006: Collaboration with Professor Luigi Giusto Spagnoli, Director of the Department of Pathological Anatomy at the University of Rome Tor Vergata, in writing the chapter entitled “Anatomo-clinical correlation between symptomatic plaques and ischemic damage” of the book “Carotid Atherosclerotic basis: pathologic basis to treatment; edited by Sangiorgi M., Holmes D., Hopkins N., Spagnoli L.G., Rosenfield L. Publisher: Taylor and Francio Medical bokks, London, U.K.
2000-2003: Volunteer attendance at the Department of Histology and Pathological Anatomy, University of Tor Vergata, Rome, Italy, with participation in the research project on cardiac tumors directed by Prof. A. Orlandi.
2000 (6 months): Volunteer attendance at the laboratories of General Pathology at the University of Tor Vergata, Rome, Italy, with participation in the mono-thematic course entitled "techniques for the study of nucleic acids", directed by Prof. V. Manzari.
EDUCATION AND TRAINING
November 29, 2019: Course “Diagnosis and management of patients with IPF: the Hub and Spoke model”, Rome, Italy.
December 13, 2018: ECM Course “Pathological Anatomy and focus on ALK, ROS1, RET and MET”, Rome, Italy.
September 2018: Course “Idiopathic Pulmonary Fibrosis”, Rome, Italy
September 29, 2017: Course “IPF: diagnostic challenge”, Rome, Italy.
September 21-22, 2017: Interactive theoretical and practical course “lung cancer: from diagnosis to therapy”, Ancona, Italy.
September 2017: participation in the course "PD-L1 in lung cancer: a guided path towards harmonized diagnostics", phase 2.
18 MAY 2017: participation in the course "consensus meeting PD-L1: an emerging reference in immuno-oncology, Rome, Italy.
7 April 2017: participation in the course "PD-L1 in lung cancer: a guided path towards harmonized diagnostics", Naples, Italy phase 1.
14-15 March 2017: participation in the course "cross talk. Pathways and perspectives in the management of alk+ and Ros1 NSCLC", Rome, Italy.
November 11-12, 2016: AIPO Lazio section meeting "a new pneumology". Rome, Italy.
September 23, 2016: course "IPF: the patient at the center", Rome, Italy.
June 5-7, 2014: participation in the 41st annual meeting of the SCUR (Society for Cutaneous Ultrastructure Research) "SKIN AGEING and CANCER: From ULTRASTRUCTURE to CLINIC", Villa Mondragone, Italy.
2012 (March 29-31): participation in the Master clinic in Respiratory Disease, Rome.
June 17-18, 2011: participation in the XXI scientific meeting of the Italian Cardiovascular Pathology Association, Villa Mondragone, Italy.
November 16-17, 2009: XI theoretical and practical refresher course in Pathological Anatomy, University of Rome Tor Vergata.
24-25 November 2008: X Theoretical updating course in Pathological Anatomy, University of Rome Tor Vergata.
26-27 November 2007: IX theoretical updating course in Pathological Anatomy, University of Rome Tor Vergata.
30-31 October 2006: VIII theoretical update course in Pathological Anatomy, University of Rome Tor Vergata.
20-21 October 2005: VII theoretical updating course in Pathological Anatomy, University of Rome Tor Vergata.
21-22 October 2004: VI Theoretical updating course in Pathological Anatomy, University of Rome Tor Vergata.
29-30 October 2003: V practical theoretical refresher course in pathological anatomy, University of Rome Tor Vergata.
2003-2008: Tor Vergata University of Rome. Attendance of the School of Specialization in Pathological Anatomy.
(2008) Experimental final thesis of specialization diploma entitled: “Expression and distribution of different alpha-actin isoforms in contractile and conduction myocardial tissue in normal and pathological conditions” with a grade of 50/50 cum laude, published in 2009 in the journal Differentiation (Alpha actin isoforms expression in human and rat adult cardiac conduction system. doi: 10.1016/j.diff.2008.12.002. Orlandi A, Hao H, Ferlosio A, Clément S, Hirota S, Spagnoli LG, Gabbiani G, Chaponnier C).
2003: Achieved the qualification to practice as a medical surgeon.
1997-2003: University of Tor Vergata, Rome, Italy. Achieved the degree in Medicine and Surgery, magna cum laude (110/110) with the discussion of the experimental thesis entitled: Cardiac myxomas: morphological study and clinicopathological correlations”, subsequently published in the American Journal of Pathology in 2005 (Increased expression and activity of matrix metalloproteinases characterize embolic cardiac myxomas. DOI: 10.1016/S0002-9440(10)62472-8. Orlandi A, Ciucci A, Ferlosio A, Pellegrino A, Chiariello L, Spagnoli LG).
1997. J.F. Kennedy Scientific High School, Rome. Obtained high school diploma (grade 60/60).
Coordination and organization of research groups and participation in them
February 2010: Appointment by the Lazio Regional Agency for Transplants and Related Pathologies as a monitoring body for the project “Identification of prognostic factors and escape mechanisms of colorectal cancer: role of NK cells derived from hematopoietic stem cells”
2015 to date: participation in the study “Histomorphometric analysis of the dentogingival unit on patients with altered passive eruption”, in collaboration with Prof. Pilloni, University “Sapienza di Roma”.
Published results: Histologic Analysis of Clinically Healthy Human Gingiva in Patients with Altered Passive Eruption. Andrea Pilloni, Lorenzo Marini, Blerina Zeza, Amedeo Ferlosio, Rustam Aghazada. Dent J (Basel). 2021 Mar 6;9(3):29. doi: 10.3390/dj9030029.
2016 to present: Participation in the Neurofibromatosis-1 research group in collaboration with the University of Padua. Reference publication: Neurofibromin Deficiency and Extracellular Matrix Cooperate to Increase Transforming Potential through FAK-Dependent Signaling. Errico A, Stocco A, Riccardi VM, Gambalunga A, Bassetto F, Grigatti M, Ferlosio A, Tadini G, Garozzo D, Ferraresi S, Trevisan A, Giustini S, Rasola A, Chiara F. Cancers (Basel). 2021 May 12;13(10):2329. doi: 10.3390/cancers13102329.
2018 to date: Study protocol “Expression of prognostic immunophenotypic markers in malignant epithelial non-small cell lung tumors” at PTV, Rome, Italy. Ethics Committee Protocol R.S. 75.18.
November 2022: Study Protocol and Research Project PNRR “Identification of new biomolecular markers of disease progression for personalized clinical management of Marfan Syndrome and bicuspid aortopathy patients”. Co-PI Prof. Augusto Orlandi, Prof. Giovanni Ruvolo; Anatomic Pathology and Cardiac Surgery Division, Tor Vergata University Polyclinic, Rome.
April 2024: Participation in the Study on Non-Profit Biological Samples “Research Selection and Characterization of Circulating Tumor Cells in Peripheral Venous Blood Samples” - CTC Project – Investigator Prof. Augusto Orlandi - U.O.S.D. Pathological Anatomy with a Histopathological Focus – Non-Profit Promoter: Fondazione PTV Policlinico Tor Vergata; R.S. 62.23.
Frontal teaching activity on site
Since 2010, Prof. Amedeo Ferlosio, on the proposal of Prof. Luigi Giusto Spagnoli, has been teaching the first lessons at the Degree Course in Medicine and Surgery at the University of Rome Tor Vergata, teaching Pathological Anatomy in the third year with particular attention to basic pathology (cellular adaptation, inflammation, cellular oncology).
In 2012, Prof. GP Palmieri, who teaches Pathological Anatomy at the Dentistry and Dental Prosthetics course at the University of Rome Tor Vergata, proposes a curricular module of 1 CFU Systematic Pathological Anatomy in addition to assigning practical exercises (1 CFU) to Dr. Amedeo Ferlosio.
In particular, the systematic part covered is: cardiovascular pathology; respiratory pathology; gastrointestinal pathology; diabetes; lymphomas of the oral cavity.
In the same year he was entrusted with the teaching of Pathological Anatomy for the Dental Hygiene course of the integrated exam “Odontostomatological diseases and elements of nutrition” (2 CFU).
Currently:
- Teaching Pathological Anatomy, Degree course in Medicine and Surgery, Pleuro-Pulmonary Pathology (2 CFU).
- Teaching Pathological Anatomy, Degree course in Dentistry and Dental Prosthetics, systematic part (1 CFU).
- Practical exercises Pathological Anatomy, Degree course in Dentistry and Dental Prosthetics, (1 CFU).
- Assignment of Pathological Anatomy for the integrated course Odontostomatological diseases and elements of nutrition, Degree course in Dental Hygiene (2 CFU).
- Practical Medicine III, Degree course in Medicine and Surgery (1 CFU).
Frontal teaching activity abroad
Teaching Pathological Anatomy, Degree Course in Dentistry and Dental Prosthetics, (2 CFU) University of Our Lady of Good Counsel, Tirana, Albania (2013 to present).
Master
Teacher of the first level university master's degree "respiratory physiopathology techniques". I edition AA 2020-21. University of Rome Tor Vergata (2CFU): teaching of functional anatomy and histology of the respiratory system.
Teacher of the first level university master's degree "respiratory physiopathology techniques". II edition AA 2021-22. University of Rome Tor Vergata (2CFU): teaching of functional anatomy and histology of the respiratory system.
Teacher of the first level university master's degree "respiratory physiopathology techniques". III edition AA 2022-23. University of Rome Tor Vergata (2CFU): teaching of functional anatomy and histology of the respiratory system.
Teacher of the first level university master's degree "respiratory physiopathology techniques". III edition AA 2023-24. University of Rome Tor Vergata (2CFU): teaching of functional anatomy and histology of the respiratory system.
Participation as a Speaker at Conferences.
October 20, 2023: Speaker at the ECM event “The multidisciplinary approach in progressive pulmonary fibrosis”. Casa dell’Aviatore, Rome.
December 12, 2022: Speaker at the ECM event “Multidisciplinary management in the diagnosis and treatment of lung cancer according to a Hospital-Territory network model”
December 6, 2021: Speaker at the event “The importance of multidisciplinary management in the diagnosis and treatment of lung cancer” Policlinico di Tor Vergata, Rome.
May 19 and June 23, 2021: Discussant at the Course “EGFR mutational dosage in lung cancer”. Drafting of the SIAPEC guidelines for the Lazio region.
November 29, 2019: Speaker at the ECM Course “Diagnosis and management of patients with IPF: the Hub and Spoke model”, Rome, Italy.
December 13, 2018: Moderator at the ECM Course “Pathological Anatomy and focus on ALK, ROS1, RET and MET”, Rome, Italy.
September 2018: Speaker at the ECM Course “Idiopathic Pulmonary Fibrosis”, Rome, Italy
September 29, 2017: Speaker at the ECM Course “IPF: diagnostic challenge”, Rome, Italy.
November 11-12, 2016: Speaker at the AIPO Lazio section meeting “a new pneumology”. Rome, Italy.
September 23, 2016: Speaker at the ECM Course “IPF: the patient at the center”, Rome, Italy.
Participation in the teaching staff of PhDs accredited by the Ministry
Participation in the 2010 board: [DOT0327400]
(registration completed on 01/26/2011) Proposing University: University of ROME "Tor Vergata" Title: "ADVANCED TECHNOLOGIES IN BIOMEDICINE"
Starting academic year: 2010 - Cycle: XXVI - Duration: 3 years.
Participation in the 2011 board: [DOT1127400]
(registration completed on 11/10/2011) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL BIOTECHNOLOGIES AND TRANSLATIONAL MEDICINE"
Starting academic year: 2011 - Cycle: XXVII - Duration: 3 years.
Participation in the 2012 college: [DOT1127400]
(registration completed on 05/02/2013) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL BIOTECHNOLOGY AND TRANSLATIONAL MEDICINE"
Academic year of start: 2012 - Cycle: XXVIII - Duration: 3 years.
Participation in the 2013 college: [DOT13ISR0U]
(registration completed on 11/09/2013) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL BIOTECHNOLOGY AND TRANSLATIONAL MEDICINE"
Academic year of start: 2013 - Cycle: XXIX - Duration: 3 years.
Participation in the 2014 college: [DOT13ISR0U]
(registration completed on 14/05/2014) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGY AND TRANSLATIONAL MEDICINE"
Starting academic year: 2014/15 - Cycle: XXX - Duration: 3 years.
Participation in the 2015 college: [DOT13ISR0U]
(registration completed on 05/05/2015) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGY AND TRANSLATIONAL MEDICINE"
Starting academic year: 2015/16 - Cycle: XXXI - Duration: 3 years.
Participation in the 2016 college: [DOT13ISR0U]
(registration completed on 03/31/2016) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGY AND TRANSLATIONAL MEDICINE"
Starting academic year: 2016/17 - Cycle: XXXII - Duration: 3 years.
Participation in the 2017 college: [DOT13ISR0U]
(registration completed on 05/09/2017) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGY AND TRANSLATIONAL MEDICINE"
Starting academic year: 2017/18 – Cycle 33: - Duration: 3 years.
Participation in the 2018 college: [DOT13ISR0U]
(registration completed on 19/03/2018) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGIES AND TRANSLATIONAL MEDICINE"
Starting academic year: 2018/19 – Cycle 34: - Duration: 3 years.
Participation in the 2019 college: [DOT13ISR0U]
(registration completed on 19/03/2019) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGIES AND TRANSLATIONAL MEDICINE"
Starting academic year: 2019/20 – Cycle 35: - Duration: 3 years.
Participation in the 2020 college: [DOT13ISR0U]
(registration completed on 06/04/2020) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGIES AND TRANSLATIONAL MEDICINE"
Starting academic year: 2020/21 – Cycle36: - Duration: 3 years.
PARTICIPATION IN THE 2021 COLLEGE: [DOT13ISR0U]
(registration completed on 23/04/2021) Proposing University: University of ROME "Tor Vergata" Title: "MEDICAL-SURGICAL BIOTECHNOLOGIES AND TRANSLATIONAL MEDICINE"
Starting academic year: 2021/2022 - Cycle: 37.
Scientific publications
1. miRNA Regulation of Cell Phenotype and Parietal Remodeling in Atherosclerotic and Non-Atherosclerotic Aortic Aneurysms: Differences and Similarities. Sonia Terriaca, Amedeo Ferlosio, Maria Giovanna Scioli, Francesca Coppa, Fabio Bertoldo, Calogera Pisano, Beatrice Belmonte, Carmela Rita Balistreri, Augusto Orlandi. Int J Mol Sci. 2024 Feb 24;25(5):2641. doi: 10.3390/ijms25052641.
2. miR-632 Induces DNAJB6 Inhibition Stimulating Endothelial-to-Mesenchymal Transition and Fibrosis in Marfan Syndrome Aortopathy. Sonia Terriaca, Maria Giovanna Scioli, Calogera Pisano, Giovanni Ruvolo, Amedeo Ferlosio, Augusto Orlandi. Int J Mol Sci. 2023 Oct 13;24(20):15133. doi: 10.3390/ijms242015133.
3. A high-performance xylene-free tissue-clearing agent for routine histology: Preliminary histomorphological results. Scioli MG, Fabbri G, Cappelli S, Savino L, Ferlosio A, Orlandi A. Ann Diagn Pathol. 2023 May 15;66:152163. doi: 10.1016/j.anndiagpath.2023.152163. Online ahead of print. PMID: 37301104
4. Ascorbic acid reduces Ropivacaine-induced myotoxicity in cultured human osteoporotic skeletal muscle cells. Scioli MG, Coniglione F, Greggi C, Evangelista L, Fiorelli E, Savino L, Ferlosio A, Piccirilli E, Gasbarra E, Iundusi R, Tarantino U, Orlandi A. BMC Musculoskelet Disord. 2023 Jul 15;24(1):576. doi: 10.1186/s12891-023-06702-5. PMID: 37454045
5. Epithelial-to-Mesenchymal Transition Gene Signature in Circulating Melanoma Cells: Biological and Clinical Relevance. Rapanotti MC, Cugini E, Campione E, Di Raimondo C, Costanza G, Rossi P, Ferlosio A, Bernardini S, Orlandi A, De Luca A, Bianchi L. Int J Mol Sci. 2023 Jul 22;24(14):11792. doi: 10.3390/ijms241411792. PMID: 37511550
6. Detection of Merkel Cell Polyomavirus (MCPyV) DNA and Transcripts in Merkel Cell Carcinoma (MCC). Passerini S, Prezioso C, Babini G, Ferlosio A, Cosio T, Campione E, Moens U, Ciotti M, Pietropaolo V. Pathogens. 2023 Jun 29;12(7):894. doi: 10.3390/pathogens12070894. PMID: 37513741
7. Increased Occurrence of Cutaneous Leiomyomas and Dermatofibromas in Patients with Uterine Leiomyomas without Fumarate Hydratase Gene Mutations. Campione E, Di Prete M, Costanza G, Saggini A, Agostinelli S, Terrinoni A, Centofanti F, Rapanotti MC, Bianchi L, Ferlosio A, Scioli MG, Orlandi A. Dermatopathology (Basel). 2023 Aug 4;10(3):231-243. doi: 10.3390/dermatopathology10030032. PMID: 37606484
8. Morelli C, Formica V, Patrikidou A, Rofei M, Shiu KK, Riondino S, Argirò R, Floris R, Ferlosio A, Orlandi A, Roselli M, Arkenau HT. Nutritional index for immune-checkpoint inhibitor in patients with metastatic gastro-esophageal junction/gastric cancer. J Gastrointest Oncol. 2022 Oct;13(5):2072-2081. doi: 10.21037/jgo-22-217. PMID: 36388663.
9. Errico A, Stocco A, Riccardi VM, Gambalunga A, Bassetto F, Grigatti M, Ferlosio A, Tadini G, Garozzo D, Ferraresi S, Trevisan A, Giustini S, Rasola A, Chiara F. Neurofibromin Deficiency and Extracellular Matrix Cooperate to Increase Transforming Potential through FAK-Dependent Signaling. Cancers (Basel). 2021 May 12;13(10):2329. doi: 10.3390/cancers13102329.
10. Pilloni A, Marini L, Zeza B, Ferlosio A, Aghazada R. Histologic Analysis of Clinically Healthy Human Gingiva in Patients with Altered Passive Eruption. Dent J (Basel). 2021 Mar 6;9(3):29. doi: 10.3390/dj9030029.
11. Efremov K, Caterini A, Petrungaro L, De Maio F, Di Prete M, Ferlosio A, Tresoldi I, Farsetti P. Clear cell hidradenoma of the hand: A case report in an 83-year old patient. Int J Surg Case Rep. 2020;75:307-310. doi: 10.1016/j.ijscr.2020.09.111. Epub 2020 Sep 19.
12. D'Amico F, Doldo E, Pisano C, Scioli MG, Centofanti F, Proietti G, Falconi M, Sangiuolo F, Ferlosio A, Ruvolo G, Orlandi A. Specific miRNA and Gene Deregulation Characterize the Increased Angiogenic Remodeling of Thoracic Aneurysmatic Aortopathy in Marfan Syndrome. Int J Mol Sci. 2020 Sep 19;21(18):6886. doi: 10.3390/ijms21186886. PMID: 32961817; PMCID: PMC7555983.
13. Ferlosio A, Doldo E, Agostinelli S, Costanza G, Centofanti F, Sidoni A,Orlandi A. Cellular retinol binding protein 1 transfection reduces proliferation and AKT-related gene expression in H460 non-small lung cancer cells. Mol Biol Rep. 2020 Sep;47(9):6879-6886. doi: 10.1007/s11033-020-05744-5. Epub 2020 Sep 9. PMID: 32909215; PMCID: PMC7561531.
14. Tarquini C, Pucci S, Scioli MG, Doldo E, Agostinelli S, D'Amico F, Bielli A, Ferlosio A, Caredda E, Tarantino U, Orlandi A. Clusterin exerts a cytoprotective and antioxidant effect in human osteoarthritic cartilage. Aging (Albany NY). 2020 Jun 9;12(11):10129-10146. doi: 10.18632/aging.103310. Epub 2020 Jun 9. PMID: 32516132; PMCID: PMC7346069.
15. Diluvio L, Caporali S, Lozzi F, Campione E, Mazzilli S, Lanna C, Bianchi L, Bernardini S, Minieri M, Mauriello A, Ferlosio A, Candi E, Terrinoni A. Birt-Hogg-Dubé syndrome, from non-invasive dermatologic assessment to gene testing, molecular and ultrastructural histologic analysis. J Eur Acad Dermatol Venereol. 2020 Apr;34(4):e206-e209. doi: 10.1111/jdv.16168. Epub 2020 Feb 5. PMID: 31876332.
16. Lancia A, Becherini C, Detti B, Bottero M, Baki M, Cancelli A, Ferlosio A, Scoccianti S, Sun R, Livi L, Ingrosso G. Radiotherapy for papillary tumor of the pineal region: A systematic review of the literature. Clin Neurol Neurosurg. 2020 Mar;190:105646. doi: 10.1016/j.clineuro.2019.105646. Epub 2019 Dec 21. PMID: 31896492.
17. Campione E, Dattola A, Di Prete M, Di Paolo D, Ferlosio A, Orlandi A, Bianchi L. Sofosbuvir induced leucocytoclasic vasculitis: a case report. BMC Dermatol. 2019 May 17;19(1):6. doi: 10.1186/s12895-019-0086-4. PMID: 31096980; PMCID: PMC6524249.
18. Toti L, Manzia TM, Roma S, Meucci R, Blasi F, Ferlosio A, Tisone G, Orlacchio A. Rare malignant glomus tumor of the stomach with liver metastases. Radiol Case Rep. 2019 Feb 2;14(4):463-467. doi: 10.1016/j.radcr.2019.01.012. PMID: 30766648; PMCID: PMC6360248.
19. Pagano A, Novegno F, Ferlosio A, Lunardi P. Repeat Bleeding 18 Years After Hemorrhagic Pilocytic Astrocytoma: Prognostic Implications of Conservative Management-Case Report and Literature Review. World Neurosurg. 2019 Mar;123:328-338. doi: 10.1016/j.wneu.2018.12.032. Epub 2018 Dec 19. PMID: 30579034.
20. Costanza G, Doldo E, Ferlosio A, Tarquini C, Passeri D, Cascella R, Bavetta M, Di Stefani A, Bonifati C, Agostinelli S, Centofanti F, Giardina E, Campione E, Bianchi L, Donati P, Morrone A, Orlandi A. Expression and potential role of cellular retinol binding protein I in psoriasis. Oncotarget. 2018 Dec 4;9(95):36736-36749. doi: 10.18632/oncotarget.26314. PMID: 30613363; PMCID: PMC6298411.
21. Ferlosio A, Di Prete M, Rossi P, Campione E, Orlandi A. Bednar Tumour Occurring after Malignant Melanoma Excision. Case Rep Pathol. 2018 Oct 1;2018:7694272. doi: 10.1155/2018/7694272. PMID: 30364040; PMCID: PMC6188857.
22. Di Prete M, Ferlosio A, Mazzilli S, Bianchi L, Orlandi A, Campione E. Non-familial porphyria cutanea tarda: a rare disease. G Ital Dermatol Venereol. 2020 Oct;155(5):687-688. doi: 10.23736/S0392-0488.18.06052-2. Epub 2018 Sep 18. PMID: 30229639.
23. Vacirca SR, Nardi P, Ferlosio A, Orlandi A, Ruvolo G. Multifocal cardiac hemangioma. J Card Surg. 2018 Jun;33(6):310-312. doi: 10.1111/jocs.13719. Epub 2018 May 27. PMID: 29806221.
24. Mazzeo M, Di Raimondo C, Vaccarini S, Ferlosio A, Orlandi A, Cantonetti M, Bianchi L. Psoriasiform sarcoidosis: an unusual variety. G Ital Dermatol Venereol. 2019 Aug;154(4):492-493. doi: 10.23736/S0392-0488.18.05756-5. Epub 2018 Jan 24. PMID: 29368850.
25. Iaquinandi A, Corrivetti F, Lunardi P, Ferlosio A, Giannini E, Novegno F. Brain Granuloma: Rare Complication of a Retained Catheter. World Neurosurg. 2018 Feb;110:210-216. doi: 10.1016/j.wneu.2017.11.066. Epub 2017 Nov 22. PMID: 29175575.
26. Ferlosio A, Bielli A, Orlandi A. Mediastinal germ cell tumors: new therapeutic insights. J Thorac Dis. 2017 Oct;9(10):3620-3622. doi: 10.21037/jtd.2017.09.46. PMID: 29268357; PMCID: PMC5723824.
27. Manenti G, Cavallo AU, Marsico S, Citraro D, Vasili E, Lacchè A, Forcina M, Ferlosio A, Rossi P, Floris R. Chronic expanding hematoma of the left flank mimicking a soft-tissue neoplasm. Radiol Case Rep. 2017 Aug 25;12(4):801-806. doi: 10.1016/j.radcr.2017.07.019. PMID: 29484075; PMCID: PMC5823383.
28. Pellegrini C, Orlandi A, Costanza G, Di Stefani A, Piccioni A, Di Cesare A, Chiricozzi A, Ferlosio A, Peris K, Fargnoli MC. Expression of IL-23/Th17-related cytokines in basal cell carcinoma and in the response to medical treatments. PLoS One. 2017 Aug 22;12(8):e0183415. doi: 10.1371/journal.pone.0183415. PMID: 28829805; PMCID: PMC5567915.
29. Ferlosio A, Orlandi A. The use of electron microscopy for the diagnosis of malignant pleural mesothelioma. J Thorac Dis. 2016 Nov;8(11):E1487-E1489. doi: 10.21037/jtd.2016.11.58. PMID: 28066639; PMCID: PMC5179440.
30. Tarquini C, Mattera R, Mastrangeli F, Agostinelli S, Ferlosio A, Bei R, Orlandi A, Tarantino U. Comparison of tissue transglutaminase 2 and bone biological markers osteocalcin, osteopontin and sclerostin expression in human osteoporosis and osteoarthritis. Amino Acids. 2017 Mar;49(3):683-693. doi: 10.1007/s00726-016-2290-4. Epub 2016 Jun 29. PMID: 27357308.
31. Cassini MA, Cerroni L, Ferlosio A, Orlandi A, Pilloni A. The gingival Stillman's clefts: histopathology and cellular characteristics. Ann Stomatol (Roma). 2016 Feb 12;6(3-4):100-3. doi: 10.11138/ads/2015.6.3.100. PMID: 26941897; PMCID: PMC4755679.
32. Doldo E, Costanza G, Ferlosio A, Pompeo E, Agostinelli S, Bellezza G, Mazzaglia D, Giunta A, Sidoni A, Orlandi A. High expression of cellular retinol binding protein-1 in lung adenocarcinoma is associated with poor prognosis. Genes Cancer. 2015 Nov;6(11-12):490-502. doi: 10.18632/genesandcancer.89. PMID: 26807202; PMCID: PMC4701228.
33. Doldo E, Costanza G, Agostinelli S, Tarquini C, Ferlosio A, Arcuri G, Passeri D, Scioli MG, Orlandi A. Vitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteins. Biomed Res Int. 2015;2015:624627. doi: 10.1155/2015/624627. Epub 2015 Mar 24. PMID: 25879031; PMCID: PMC4387950.
34. Scioli MG, Bielli A, Arcuri G, Ferlosio A, Orlandi A. Ageing and microvasculature. Vasc Cell. 2014 Sep 16;6:19. doi: 10.1186/2045-824X-6-19. PMID: 25243060; PMCID: PMC4169693.
35. Doldo E, Costanza G, Ferlosio A, Passeri D, Bernardini S, Scioli MG, Mazzaglia D, Agostinelli S, Del Bufalo D, Czernobilsky B, Orlandi A. CRBP-1 expression in ovarian cancer: a potential therapeutic target. Anticancer Res. 2014 Jul;34(7):3303-12. PMID: 24982334.
36. Romaniello F, Mazzaglia D, Pellegrino A, Grego S, Fiorito R, Ferlosio A, Chiariello L, Orlandi A. Aortopathy in Marfan syndrome: an update. Cardiovasc Pathol. 2014 Sep-Oct;23(5):261-6. doi: 10.1016/j.carpath.2014.04.007. Epub 2014 May 6. PMID: 24925629.
37. Scioli MG, Bielli A, Agostinelli S, Tarquini C, Arcuri G, Ferlosio A, Costanza G, Doldo E, Orlandi A. Antioxidant treatment prevents serum deprivation- and TNF-α-induced endothelial dysfunction through the inhibition of NADPH oxidase 4 and the restoration of β-oxidation. J Vasc Res. 2014;51(5):327-37. doi: 10.1159/000365926. Epub 2014 Nov 7. PMID: 25401479.
38. Ferlosio A, Manzia TM, Anemona L, Tisone G, Orlandi A. Myopericytoma of the liver hilus: a case report. Turk Patoloji Derg. 2014;30(3):215-9. doi: 10.5146/tjpath.2014.01256. PMID: 25301166.
39. Tarantino U, Celi M, Rao C, Feola M, Cerocchi I, Gasbarra E, Ferlosio A, Orlandi A. Hip osteoarthritis and osteoporosis: clinical and histomorphometric considerations. Int J Endocrinol. 2014;2014:372021. doi: 10.1155/2014/372021. Epub 2014 Apr 14. PMID: 24829574; PMCID: PMC4009293.
40. Sconocchia G, Eppenberger-Castori S, Zlobec I, Karamitopoulou E, Arriga R, Coppola A, Caratelli S, Spagnoli GC, Lauro D, Lugli A, Han J, Iezzi G, Ferrone C, Ferlosio A, Tornillo L, Droeser R, Rossi P, Attanasio A, Ferrone S, Terracciano L. HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker. Neoplasia. 2014 Jan;16(1):31-42. doi: 10.1593/neo.131568. PMID: 24563618; PMCID: PMC3924546.
41. Ferlosio A, Doldo E, Polisca P, Orlandi A. Low-grade fibromyxoid sarcoma: an unusual cardiac location. Cardiovasc Pathol. 2013 May-Jun;22(3):e15-7. doi: 10.1016/j.carpath.2012.11.004. Epub 2013 Jan 3. PMID: 23290535.
42. Ferlosio A, Orlandi A. Diabetes and aging: a different phenotypic commitment of circulating and resident stem cells? Acta Diabetol. 2012 Dec;49(6):493-4. doi: 10.1007/s00592-012-0432-z. Epub 2012 Oct 5. PMID: 23053879.
43. Ferlosio A, Orlandi A. Stem cells, aging and pulmonary vascular remodelling. Sarcoidosis Vasc Diffuse Lung Dis. 2012 Oct;29(2):159-60. PMID: 23461081.
44. Ferlosio A, Arcuri G, Doldo E, Scioli MG, De Falco S, Spagnoli LG, Orlandi A. Age-related increase of stem marker expression influences vascular smooth muscle cell properties. Atherosclerosis. 2012 Sep;224(1):51-7. doi: 10.1016/j.atherosclerosis.2012.07.016. Epub 2012 Jul 17. PMID: 22857896.
45. Loreto C, Orlandi A, Ferlosio A, Djinovic R, Basic D, Bettocchi C, Rutigliano M, Barbagli G, Vespasiani G, Caltabiano R, Musumeci G, Sansalone S. Cryopreserved penile tunica albuginea for allotransplantation: a morphological and ultrastructural investigation. J Sex Med. 2012 Sep;9(9):2378-88. doi: 10.1111/j.1743-6109.2012.02789.x. Epub 2012 May 22. PMID: 22616821.
46. Tarantino U, Ferlosio A, Arcuri G, Spagnoli LG, Orlandi A. Transglutaminase 2 as a biomarker of osteoarthritis: an update. Amino Acids. 2013 Jan;44(1):199-207. doi: 10.1007/s00726-011-1181-y. Epub 2011 Dec 3. PMID: 22139411.
47. Di Stefani A, Gabellini M, Ferlosio A, Spagnoli LG, Chimenti S, Orlandi A. Cerebriform plantar hyperplasia: the clinico-pathological hallmark of Proteus syndrome. Acta Derm Venereol. 2011 Sep;91(5):580-1. doi: 10.2340/00015555-1087. PMID: 21681363.
48. Perovic SV, Sansalone S, Djinovic R, Ferlosio A, Vespasiani G, Orlandi A. Penile enhancement using autologous tissue engineering with biodegradable scaffold: a clinical and histomorphometric study. J Sex Med. 2010 Sep;7(9):3206-15. doi: 10.1111/j.1743-6109.2009.01545.x. PMID: 20796201.
49. Orlandi A, Ferlosio A, Roselli M, Chiariello L, Spagnoli LG. Cardiac sarcomas: an update. J Thorac Oncol. 2010 Sep;5(9):1483-9. doi: 10.1097/JTO.0b013e3181e59a91. PMID: 20651614.
50. Orlandi A, Ferlosio A, Arcuri G, Scioli MG, De Falco S, Spagnoli LG. Flt-1 expression influences apoptotic susceptibility of vascular smooth muscle cells through the NF-kappaB/IAP-1 pathway. Cardiovasc Res. 2010 Jan 1;85(1):214-23. doi: 10.1093/cvr/cvp288. PMID: 19720604.
51. Orlandi A, Hao H, Ferlosio A, Clément S, Hirota S, Spagnoli LG, Gabbiani G, Chaponnier C. Alpha actin isoforms expression in human and rat adult cardiac conduction system. Differentiation. 2009 Apr;77(4):360-8. doi: 10.1016/j.diff.2008.12.002. Epub 2009 Feb 4. PMID: 19281784.
52. Orlandi A, Costantini S, Campione E, Ferlosio A, Amantea A, Bianchi L, Chimenti S, Spagnoli LG. Relation between animal-type melanoma and reduced nuclear expression of glutathione S-transferase pi. Arch Dermatol. 2009 Jan;145(1):55-62. doi: 10.1001/archderm.145.1.55. PMID: 19153344.
53. Orlandi A, Di Lascio A, Francesconi A, Scioli MG, Arcuri G, Ferlosio A, Spagnoli LG. Stem cell marker expression and proliferation and apoptosis of vascular smooth muscle cells. Cell Cycle. 2008 Dec 15;7(24):3889-97. doi: 10.4161/cc.7.24.7323. Epub 2008 Dec 30. PMID: 19098424.
54. Rogliani P, Mura M, Mattia P, Ferlosio A, Farinelli G, Mariotta S, Graziano P, Pezzuto G, Ricci A, Saltini C, Orlandi A. HRCT and histopathological evaluation of fibrosis and tissue destruction in IPF associated with pulmonary emphysema. Respir Med. 2008 Dec;102(12):1753-61. doi: 10.1016/j.rmed.2008.07.010. Epub 2008 Aug 23. PMID: 18723334.
55. Orlandi A, Francesconi A, Ferlosio A, Di Lascio A, Marcellini M, Pisano C, Spagnoli LG. Propionyl-L-carnitine prevents age-related myocardial remodeling in the rabbit. J Cardiovasc Pharmacol. 2007 Aug;50(2):168-75. doi: 10.1097/FJC.0b013e31805d8ee9. PMID: 17703133.
56. Orlandi A, Ferlosio A, Ciucci A, Francesconi A, Lifschitz-Mercer B, Gabbiani G, Spagnoli LG, Czernobilsky B. Cellular retinol binding protein-1 expression in endometrial hyperplasia and carcinoma: diagnostic and possible therapeutic implications. Mod Pathol. 2006 Jun;19(6):797-803. doi: 10.1038/modpathol.3800586. PMID: 16575402.
57. Orlandi A, Ciucci A, Ferlosio A, Genta R, Spagnoli LG, Gabbiani G. Cardiac myxoma cells exhibit embryonic endocardial stem cell features. J Pathol. 2006 Jun;209(2):231-9. doi: 10.1002/path.1959. PMID: 16508920.
58. Orlandi A, Ferlosio A, Gabbiani G, Spagnoli LG, Ehrlich PH. Phenotypic heterogeneity influences the behavior of rat aortic smooth muscle cells in collagen lattice. Exp Cell Res. 2005 Dec 10;311(2):317-27. doi: 10.1016/j.yexcr.2005.10.008. Epub 2005 Nov 2. PMID: 16263112.
59. Orlandi A, Ferlosio A, Angeloni C, Ciucci A, Giusto Spagnoli L. I tumori cardiaci [Cardiac tumors]. Pathologica. 2005 Jun;97(3):115-23. Italian. PMID: 16259277.
60. Orlandi A, Ciucci A, Ferlosio A, Pellegrino A, Chiariello L, Spagnoli LG. Increased expression and activity of matrix metalloproteinases characterize embolic cardiac myxomas. Am J Pathol. 2005 Jun;166(6):1619-28. doi: 10.1016/S0002-9440(10)62472-8. PMID: 15920147; PMCID: PMC1602416.
61. Orlandi A, Pucci S, Ciucci A, Pichiorri F, Ferlosio A, Spagnoli LG. Modulation of clusterin isoforms is associated with all-trans retinoic acid-induced proliferative arrest and apoptosis of intimal smooth muscle cells. Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):348-53. doi: 10.1161/01.ATV.0000152609.28569.e1. Epub 2004 Dec 9. PMID: 15591223.
62. Orlandi A, Ferlosio A, Ciucci A, Pellegrino A, Spagnoli LG. Unusual cardiac tumour with perivascular myoid differentiation: a case report. J Clin Pathol. 2004 Dec;57(12):1338-40. doi: 10.1136/jcp.2004.020081. PMID: 15563682; PMCID: PMC1770506.
63. Orlandi A, Francesconi A, Marcellini M, Ferlosio A, Spagnoli LG. Role of ageing and coronary atherosclerosis in the development of cardiac fibrosis in the rabbit. Cardiovasc Res. 2004 Dec 1;64(3):544-52. doi: 10.1016/j.cardiores.2004.07.024. PMID: 15537508.
64. Orlandi A, Ferlosio A, Ciucci A, Sesti F, Lifschitz-Mercer B, Gabbiani G, Spagnoli LG, Czernobilsky B. Cellular retinol-binding protein-1 expression in endometrial stromal cells: physiopathological and diagnostic implications. Histopathology. 2004 Nov;45(5):511-7. doi: 10.1111/j.1365-2559.2004.01963.x. PMID: 15500655.
65. Orlandi A, Bianchi L, Ferlosio A, Innocenzi I, Spagnoli LG. The origin of osteoclast-like giant cells in atypical fibroxanthoma. Histopathology. 2003 Apr;42(4):407-10. doi: 10.1046/j.1365-2559.2003.01552_4.x. PMID: 12653956.
66. Orlandi A, Ferlosio A, Pellegrino A, Spagnoli LG. Right atrial hemangioma: clinicopathological considerations of a case. Interact Cardiovasc Thorac Surg. 2003 Mar;2(1):38-9. doi: 10.1016/S1569-9293(02)00095-6. PMID: 17669983.
67. Orlandi A, Ferlosio A, Dell'Anna V, Quitadamo R, Pellegrino A, Spagnoli LG. Undifferentiated sarcoma of the heart: a rare clinicopathologic presentation. J Thorac Cardiovasc Surg. 2002 Jul;124(1):192-3. doi: 10.1067/mtc.2002.122787. PMID: 12091831.